1. Gene
  2. LST1 - leukocyte specific transcript 1 Gene

LST1 - leukocyte specific transcript 1 Gene

中文名称:白细胞特异性转录物 1

种属: Homo sapiens

同用名: B144; LST-1; D6S49E

基因 ID: 7940 | 基因类型: protein coding

关于 LST1

Cytogenetic location: 6p21.33 Genomic coordinates (GRCh38): 6:31,586,277-31,588,909 (from NCBI)

This gene has 21 transcripts (splice variants), 1 gene allele and 44 orthologues. Biased expression in bone marrow (RPKM 68.1), spleen (RPKM 43.9) and 13 other tissues.

功能概要

该基因编码的蛋白质是一种能抑制淋巴细胞增殖的膜蛋白。脂多糖、干扰素-γ 和细菌可增强该基因的表达。已发现该基因编码不同亚型的几种转录变体。[RefSeq 提供,2011 年 10 月]

The protein encoded by this gene is a membrane protein that can inhibit the proliferation of lymphocytes. Expression of this gene is enhanced by lipopolysaccharide, interferon-gamma, and bacteria. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

LST1 基因产物(6)

mRNA Protein Name
NM_001166538.1 NP_001160010.1 leukocyte-specific transcript 1 protein isoform 6
NM_007161.3 NP_009092.3 leukocyte-specific transcript 1 protein isoform 1
NM_205837.3 NP_995309.2 leukocyte-specific transcript 1 protein isoform 2
NM_205838.3 NP_995310.2 leukocyte-specific transcript 1 protein isoform 3
NM_205839.3 NP_995311.2 leukocyte-specific transcript 1 protein isoform 4
NM_205840.2 NP_995312.2 leukocyte-specific transcript 1 protein isoform 5

LST1 蛋白结构

LST1

LST1: LST-1 protein (16 - 97)

  • 0
  • 97 a.a.
蛋白主名 其他名称

leukocyte-specific transcript 1 protein

lymphocyte antigen 117

关联疾病

疾病名称 别名
Cleft Palate, Isolated

Cleft Palate

Isolated Cleft Palate

CPI

Cp

Palatoschisis

Cleft Palate Isolated

Uranostaphyloschisis

Congenital Fissure Of Palate

Cleft Of Secondary Palate

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus LST1 RGD RGD:620077
Bos taurus LST1 VGNC VGNC:107291
Mus musculus LST1 MGD MGI:1096324