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  3. Pi4kb - phosphatidylinositol 4-kinase beta Gene

Pi4kb - phosphatidylinositol 4-kinase beta Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：磷脂酰肌醇 4-激酶 β

种属: Rattus norvegicus

同用名: Pik4cb

基因 ID: 81747 | 基因类型: protein coding

关于 Pi4kb

Primary_assembly 2: 182,540,567-182,588,488 forward strand.mRatBN7.2:CM026975.1

This gene has 6 transcripts (splice variants), 213 orthologues, 9 paralogues and is associated with 8 phenotypes. Biased expression in Adrenal (RPKM 175.8), Kidney (RPKM 157.8) and 9 other tissues.

功能概要

该基因编码的蛋白可启动 1-磷脂酰肌醇 4-激酶活性。预计参与磷脂酰肌醇磷酸盐生物合成过程和磷脂酰肌醇介导的信号传导。位于胞质溶胶和质膜中。与人 PI4KB（磷脂酰肌醇 4-激酶 β）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables 1-phosphatidylinositol 4-kinase activity. Predicted to be involved in phosphatidylinositol phosphate biosynthetic process and phosphatidylinositol-mediated signaling. Located in cytosol and plasma membrane. Orthologous to human PI4KB (phosphatidylinositol 4-kinase beta). [provided by Alliance of Genome Resources, Apr 2022]

Pi4kb 基因产物(2)

mRNA Protein Name
NM_031083.2 NP_112345.1 phosphatidylinositol 4-kinase beta
NM_031083.2 NP_112345.1 phosphatidylinositol 4-kinase beta

Pi4kb 蛋白结构

PI4KB_NTD

PI4KB_NTD: cd22246 (26 - 90)

PI4Kc_III_beta

PI4Kc_III_beta: cd05168 (553 - 861)

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  • 862 a.a.
蛋白主名 其他名称

phosphatidylinositol 4-kinase beta

PI4K-beta

PI4Kbeta

catalytic phosphatidylinositol 4-kinase beta

phosphatidylinositol 4-kinase, catalytic, beta polypeptide

ptdIns 4-kinase beta

相关产品

Pre-clinical Phase
生物活性分子 (9)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-108313 T-00127_HEV1 Inhibitor 99.97% 否
HY-22055B AN-12-H5 intermediate-1 99.72% 否
HY-100603 GSK-F1 Inhibitor 95.00% 否
HY-120900 AN-12-H5 Inhibitor 98.03% 否
HY-W047496 AN-12-H5 intermediate-2 ≥97.0% 否
HY-RS10469 PI4KB Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS10470 Pi4kb Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS10471 Pi4kb Rat Pre-designed siRNA Set A Pre-designed Sets / 否
HY-W451820 AN-12-H5 intermediate-3 95.82% 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pi4kb NCBI NCBI:5298
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