1. Apoptosis Metabolic Enzyme/Protease
  2. Glutathione Peroxidase Ferroptosis
  3. GPX4 activator 1

GPX4 activator 1 (Compound A9) 是一种 GPX4 变构激活剂 (Kd = 5.86 μM, EC50 = 19.19 μM)。GPX4 activator 1 可以选择性地作用于铁死亡,并阻止由铁死亡诱导剂引起的细胞内脂质过氧化物的积累。

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GPX4 activator 1 Chemical Structure

GPX4 activator 1 Chemical Structure

CAS No. : 1030098-18-0

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

GPX4 activator 1 (Compound A9) is a allosteric activator of GPX4 (Kd = 5.86 μM, EC50 = 19.19 μM). GPX4 activator 1 can selectively act on ferroptosis and prevent the accumulation of intracellular lipid peroxides caused by ferroptosis inducers[1].

分子量

414.52

Formula

C20H26N6O2S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
GPX4 activator 1
目录号:
HY-161928
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