2. Metabolic Enzyme/Protease Membrane Transporter/Ion Channel
  3. Ser/Thr Protease Potassium Channel
  4. HG1 Toxin

HG1 Toxin 是一种存在于蝎子 Heterometrus fulvipes 的毒液中的肽， 具有抑制钾通道 Kv1.3 (potassium channel Kv1.3) 的活性。HG1 Toxin 还具有抑制胰蛋白酶 (trypsin) 的活性 (Ki=107 nM)，可用于自身免疫疾病的研究。

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Custom Peptide Synthesis

HG1 Toxin Chemical Structure

HG1 Toxin Chemical Structure

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规格 是否有货
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HG1 Toxin 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

HG1 Toxin is a peptide found in the venom of the scorpion Heterometrus fulvipes, which has the activity of inhibiting potassium channel Kv1.3. HG1 Toxin also has the activity of inhibiting trypsin (Ki=107 nM) and can be used in the study of autoimmune diseases[1].

分子量

7741.62

Formula

C337H503N103O97S6
Sequence

Gly-His-His-Asn-Arg-Val-Asn-Cys-Leu-Leu-Pro-Pro-Lys-Thr-Gly-Pro-Cys-Lys-Gly-Ser-Phe-Ala-Arg-Tyr-Tyr-Phe-Asp-Ile-Glu-Thr-Gly-Ser-Cys-Lys-Ala-Phe-Ile-Tyr-Gly-Gly-Cys-Glu-Gly-Asn-Ser-Asn-{Asn(GlcNAc)}-Phe-Ser-Glu-Lys-His-His-Cys-Glu-Lys-Arg-Cys-Arg-Gly-Phe-Arg-Lys-Phe-Gly-Gly-Lys (disulfide bridge: Cys8-Cys58;Cys17-Cys54;Cys33-Cys41)
Sequence Shortening

GHHNRVNCLLPPKTGPCKGSFARYYFDIETGSCKAFIYGGCEGNSN-{Asn(GlcNAc)}-FSEKHHCEKRCRGFRKFGGK (disulfide bridge: Cys8-Cys58;Cys17-Cys54;Cys33-Cys41)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

HG1 Toxin 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HG1 ToxinSer/Thr ProteasePotassium ChannelSerine proteasesSerine endopeptidasesThreonine proteasesKcsAPeptidespotassium channelstrypsinautoimmune diseasesinhibitorInhibitorinhibit

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产品名称：
HG1 Toxin
目录号：
HY-P10572
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