2. Epigenetics Cell Cycle/DNA Damage
  3. Histone Demethylase HDAC
  4. LSD1/HDAC6-IN-1

LSD1/HDAC6-IN-1 是一种具有口服活性的组蛋白去甲基化酶 LSD1 和组蛋白去乙酰酶 HDAC6 (LSD1/HDAC6) 双重抑制剂，具有抗肿瘤活性。LSD1/HDAC6-IN-1 可用于多发性骨髓瘤 (MM) 的研究。

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LSD1/HDAC6-IN-1 Chemical Structure

LSD1/HDAC6-IN-1 Chemical Structure

CAS No. : 2738306-38-0

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LSD1/HDAC6-IN-1 相关抗体

Top Publications Citing Use of Products

查看 Histone Demethylase 亚型特异性产品:

查看所有亚型
KDM1/LSD1 KDM2 KDM3 KDM4 KDM5 KDM6

查看 HDAC 亚型特异性产品:

查看所有亚型
HDAC HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HDAC7 HDAC8 HDAC9 HDAC10 HDAC11 HD1 HD2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

LSD1/HDAC6-IN-1 is an orally active dual inhibitor of lysine specific demethylase 1(LSD1)/Histone deacetylase 6 (HDAC6), with anti-tumor activity. LSD1/HDAC6-IN-1 can be used for the research of multiple myeloma (MM)[1].

IC50 & Target

KDM1/LSD1

 

HDAC6

 

体外研究
(In Vitro)

LSD1/HDAC6-IN-1 shows superior potency in multiple MM lines[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

LSD1/HDAC6-IN-1 相关抗体:
体内研究
(In Vivo)

LSD1/HDAC6-IN-1 is efficacy in the MM.1S xenograft model[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

407.55

Formula

C25H33N3O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

LSD1/HDAC6-IN-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LSD1/HDAC6-IN-12738306-38-0Histone DemethylaseHDACHistone deacetylasesmultiplemyelomaIMiDshistonedeacetylase6HDAC6lysine-specificdemethylase 1immunomodulatoryimideInhibitorinhibitorinhibit

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