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  4. LY 190388

LY 190388是一种含有青霉胺的恩可法肽类似物，具有μ受体激动剂活性。LY 190388在通过脑室内给药后，在抑制小鼠扭体反应方面表现出止痛效果。LY 190388的镇痛效果并非通过δ受体激动剂作用，而是由其μ受体激动剂活性所引起。LY 190388与δ受体拮抗剂ICI 174864共同使用时，会产生附加的镇痛效果。

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LY 190388 Chemical Structure

LY 190388 Chemical Structure

CAS No. : 105496-35-3

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LY 190388 相关抗体

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  • 生物活性

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生物活性

LY 190388 is a penicillamine-containing enkefa peptide analog with μ receptor agonist activity. LY 190388 showed analgesic effect in inhibiting the writhing response in mice after intracerebroventricular administration. The analgesic effect of LY 190388 is not caused by its δ receptor agonist action, but by its μ receptor agonist activity. When LY 190388 is used together with the δ receptor antagonist ICI 174864, an additive analgesic effect is produced[1].

分子量

615.74

Formula

C30H41N5O7S
CAS 号
Sequence

Tyr-{d-Pen}-Gly-Phe-{d-Val}
Sequence Shortening

Y-{d-Pen}-GF-{d-Val}
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

LY 190388 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LY 190388105496-35-3LY190388LY-190388OthersInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-P1617
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