2. Academic Validation
  3. Structural studies of cysteine proteases and their inhibitors

Structural studies of cysteine proteases and their inhibitors

  • Acta Biochim Pol. 2001;48(1):1-20.
Z Grzonka 1,  E Jankowska,  F Kasprzykowski,  R Kasprzykowska,  L Lankiewicz,  W Wiczk,  E Wieczerzak,  J Ciarkowski,  P Drabik,  R Janowski,  M Kozak,  M Jaskólski,  A Grubb
Affiliations

Affiliation

  • 1 Department of Organic Chemistry, Faculty of Chemistry, University of Gdańsk, Poland. grzonka@chemik.chem.univ.gda.pl
PMID: 11440158
Abstract

Cysteine proteases (CPs) are responsible for many biochemical processes occurring in living organisms and they have been implicated in the development and progression of several diseases that involve abnormal protein turnover. The activity of CPs is regulated among Others by their specific inhibitors: cystatins. The main aim of this review is to discuss the structure-activity relationships of cysteine proteases and cystatins, as well as of some synthetic inhibitors of cysteine proteases structurally based on the binding fragments of cystatins.

Figures
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z