2. Academic Validation
  3. Marsdenosides A-H, polyoxypregnane glycosides from Marsdenia tenacissima

Marsdenosides A-H, polyoxypregnane glycosides from Marsdenia tenacissima

  • Phytochemistry. 2005 May;66(9):1040-51. doi: 10.1016/j.phytochem.2005.03.018.
Jun Deng 1,  Zhixin Liao,  Daofeng Chen
Affiliations

Affiliation

  • 1 Department of Pharmacognosy, School of Pharmacy, Fudan University, Shanghai 200032, PR China.
PMID: 15896374 DOI: 10.1016/j.phytochem.2005.03.018
Abstract

Eight polyoxypregnane glycosides, marsdenosides A-H, were isolated from the CHCl(3)-soluble fraction of the ethanolic extract of the stem of Marsdenia tenacissima, along with six known glycosides and two known polyoxypregnane aglycones. Three polyoxypregnanes, 12beta-O-2-methylbutyryl-tenacigenin A, 11alpha,12beta-di-O-acetyltenacigenin B, and 11alpha-O-tigloyltenacigenin B were also obtained. Their structures were established on the basis of spectroscopic analysis and chemical evidence.

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