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  3. Two flavonoid dimers from Sarcandra hainanensis (PEI) SWAMY et BAILEY

Two flavonoid dimers from Sarcandra hainanensis (PEI) SWAMY et BAILEY

  • Chem Pharm Bull (Tokyo). 2009 Jul;57(7):743-6. doi: 10.1248/cpb.57.743.
Cong-Mei Cao 1,  Yong Peng,  Li-Jia Xu,  Ya-Jun Wang,  Jun-Shan Yang,  Pei-Gen Xiao
Affiliations

Affiliation

  • 1 Institute of Medicinal Plant Development, Chinese Academy of Medical Science, Peking Union Medical College.
PMID: 19571424 DOI: 10.1248/cpb.57.743
Abstract

Two new flavonoid dimers (1, 2) consisting of flavan-chalcone together with three known compounds (3-5) were isolated from the ethanol extract of the whole Plants of Sarcandra hainanensis. Their structures were determined by extensive spectroscopic analysis. Human immunodeficiency virus-1 integrase inhibition activities of compounds 1 and 2 were evaluated and they showed weak activities with IC(50) at 18.05 and 25.27 muM, respectively.

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