2. Academic Validation
  3. Discovery of small molecules that bind to K-Ras and inhibit Sos-mediated activation

Discovery of small molecules that bind to K-Ras and inhibit Sos-mediated activation

  • Angew Chem Int Ed Engl. 2012 Jun 18;51(25):6140-3. doi: 10.1002/anie.201201358.
Qi Sun 1,  Jason P Burke,  Jason Phan,  Michael C Burns,  Edward T Olejniczak,  Alex G Waterson,  Taekyu Lee,  Olivia W Rossanese,  Stephen W Fesik
Affiliations

Affiliation

  • 1 Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
PMID: 22566140 DOI: 10.1002/anie.201201358
Figures
Products
  • Cat. No.
    Product Name
    Description
    Target
    Research Area
  • HY-18674
    98.00%, K-Ras抑制剂
    Ras
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