2. Academic Validation
  3. The ORF3a protein of SARS-CoV-2 induces apoptosis in cells

The ORF3a protein of SARS-CoV-2 induces apoptosis in cells

  • Cell Mol Immunol. 2020 Aug;17(8):881-883. doi: 10.1038/s41423-020-0485-9.
Yujie Ren 1 2 3,  Ting Shu 2 4 5,  Di Wu 2 4,  Jingfang Mu 2 4,  Chong Wang 1 2 3,  Muhan Huang 2 4,  Yang Han 2 4 5,  Xue-Yi Zhang 2 6,  Wei Zhou 1,  Yang Qiu 7 8 9 10,  Xi Zhou 11 12 13 14 15 16
Affiliations

Affiliations

  • 1 Center for Precision Translational Medicine of Wuhan Institute of Virology & Guangzhou Women and Children's Medical Center, Guangzhou Women and Children's Medical Center, Guangzhou, Guangdong, 510120, China.
  • 2 State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences (CAS), Wuhan, Hubei, 430071, China.
  • 3 Center for Precision Translational Medicine of Wuhan Institute of Virology & Guangzhou Women and Children's Medical Center, Wuhan Institute of Virology, CAS, Wuhan, Hubei, 430071, China.
  • 4 Joint Laboratory of Infectious Diseases and Health, Wuhan Institute of Virology & Wuhan Jinyintan Hospital, CAS, Wuhan, Hubei, 430023, China.
  • 5 Center for Translational Medicine, Wuhan Jinyintan Hospital, Wuhan, Hubei, 430023, China.
  • 6 State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, Hubei, 430072, China.
  • 7 State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences (CAS), Wuhan, Hubei, 430071, China. yangqiu@wh.iov.cn.
  • 8 Joint Laboratory of Infectious Diseases and Health, Wuhan Institute of Virology & Wuhan Jinyintan Hospital, CAS, Wuhan, Hubei, 430023, China. yangqiu@wh.iov.cn.
  • 9 Center for Translational Medicine, Wuhan Jinyintan Hospital, Wuhan, Hubei, 430023, China. yangqiu@wh.iov.cn.
  • 10 University of Chinese Academy of Sciences, Beijing, 100049, China. yangqiu@wh.iov.cn.
  • 11 State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences (CAS), Wuhan, Hubei, 430071, China. zhouxi@wh.iov.cn.
  • 12 Center for Precision Translational Medicine of Wuhan Institute of Virology & Guangzhou Women and Children's Medical Center, Wuhan Institute of Virology, CAS, Wuhan, Hubei, 430071, China. zhouxi@wh.iov.cn.
  • 13 Joint Laboratory of Infectious Diseases and Health, Wuhan Institute of Virology & Wuhan Jinyintan Hospital, CAS, Wuhan, Hubei, 430023, China. zhouxi@wh.iov.cn.
  • 14 Center for Translational Medicine, Wuhan Jinyintan Hospital, Wuhan, Hubei, 430023, China. zhouxi@wh.iov.cn.
  • 15 State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, Hubei, 430072, China. zhouxi@wh.iov.cn.
  • 16 University of Chinese Academy of Sciences, Beijing, 100049, China. zhouxi@wh.iov.cn.
PMID: 32555321 DOI: 10.1038/s41423-020-0485-9
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