1. Academic Validation
  2. Runx2 (Runt-Related Transcription Factor 2) Links the DNA Damage Response to Osteogenic Reprogramming and Apoptosis of Vascular Smooth Muscle Cells

Runx2 (Runt-Related Transcription Factor 2) Links the DNA Damage Response to Osteogenic Reprogramming and Apoptosis of Vascular Smooth Muscle Cells

  • Arterioscler Thromb Vasc Biol. 2021 Apr;41(4):1339-1357. doi: 10.1161/ATVBAHA.120.315206.
Andrew M Cobb 1 Syabira Yusoff 1 Robert Hayward 1 Sadia Ahmad 1 Mengxi Sun 1 Anja Verhulst 2 Patrick C D'Haese 2 Catherine M Shanahan 1
Affiliations

Affiliations

  • 1 BHF Centre of Research Excellence, School of Cardiovascular Medicine and Sciences, King's College London, The James Black Centre, United Kingdom (A.M.C., S.Y., R.H., S.A., M.S., C.M.S.).
  • 2 Laboratory of Pathophysiology, Department of Biomedical Sciences, University of Antwerp, Wilrijk, Belgium (A.V., P.C.D.).
Abstract

[Figure: see text].

Keywords

DNA damage; aging; apoptosis; poly ADP ribosylation; vascular calcification.

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