2. Antibody-drug Conjugate/ADC Related
  3. ADC Linker
  4. Methyltetrazine-PEG4-SS-NHS ester

Methyltetrazine-PEG4-SS-NHS ester 

目录号: HY-133466 纯度: ≥95.0%
COA 产品使用指南

摩尔计算器

Methyltetrazine-PEG4-SS-NHS ester 是一种可降解 (cleavable) 的含 4 个单元 PEG 的 ADC linker，可用于合成抗体偶联活性分子 (ADC)。Methyltetrazine-PEG4-SS-NHS ester 是一种点击化学试剂。它含有 Tetrazine 基团，可以和含有 TCO 基团的分子发生逆电子需求 Diels-Alder 反应 (iEDDA)。

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Methyltetrazine-PEG4-SS-NHS ester Chemical Structure

Methyltetrazine-PEG4-SS-NHS ester Chemical Structure

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规格 价格 是否有货 数量
1 mg ￥1100
In-stock
5 mg ￥2720
In-stock
10 mg ￥4400
In-stock
50 mg   询价  
100 mg   询价  

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Customer Review

Methyltetrazine-PEG4-SS-NHS ester 相关抗体

Top Publications Citing Use of Products

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Methyltetrazine-PEG4-SS-NHS ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Methyltetrazine-PEG4-SS-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

IC50 & Target

Disulfide Cleavable Linker

 

Cleavable Linker

 

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Methyltetrazine-PEG4-SS-NHS ester 相关抗体:
分子量

737.84

Formula

C31H43N7O10S2
性状

油状物

颜色

Pink to red

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Pure form -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

纯度: ≥95.0%

COA (280 KB) HNMR (345 KB)

产品使用指南 (1538 KB)
参考文献

Methyltetrazine-PEG4-SS-NHS ester 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Methyltetrazine-PEG4-SS-NHS esterADC LinkerAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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产品名称：
Methyltetrazine-PEG4-SS-NHS ester
目录号：
HY-133466
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