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  3. MOR agonist-3

MOR agonist-3 (Compound 84) 是一种 D3R/MOR 拮抗剂 (Ki 分别为 55.2 nM 和 382 nM)。MOR agonist-3 通过 MOR (HY-149337) 部分激动剂产生镇痛作用的潜力,并通过 D3R 拮抗剂减少阿片类药物滥用。MOR agonist-3 能够用于炎症治疗和神经性疼痛研究。

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MOR agonist-3 Chemical Structure

MOR agonist-3 Chemical Structure

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生物活性

MOR agonist-3 (Compound 84) is a D3R/MOR antagonist (Ki 382 nM and 55.2 nM respectively). MOR agonist-3 has the potential to produce analgesic effects through MOR (μ-opioid receptor) (HY-149337) partial agonists and to reduce opioid abuse through D3R antagonists. MOR agonist-3 can be used in the treatment of inflammation and neuropathic pain research[1].

分子量

428.57

Formula

C28H32N2O2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

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参考文献

MOR agonist-3 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
MOR agonist-3
目录号:
HY-155707
需求量: