2. Metabolic Enzyme/Protease
  3. Ser/Thr Protease
  4. Patamostat hydrochloride

Patamostat hydrochloride  (Synonyms: E-3123 hydrochloride)

目录号: HY-114080B
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摩尔计算器

Patamostat (E-3123) hydrochloride 是一种有效的蛋白酶 (protease) 抑制剂。Patamostat hydrochloride 有效抑制胰蛋白酶，纤溶酶和凝血酶，IC50 值分别为 39 nM，950 nM 和 1.9 μM。Patamostat hydrochloride 有潜力用于急性胰腺炎的研究。

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Patamostat hydrochloride Chemical Structure

Patamostat hydrochloride Chemical Structure

CAS No. : 3031765-17-7

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Patamostat hydrochloride 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

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生物活性

Patamostat hydrochloride is a potent protease inhibitor. Patamostat hydrochloride potently inhibits trypsin, plasmin and thrombin with IC50s of 39 nM, 950 nM and 1.9 μM, respectively. Patamostat hydrochloride may possess suppressing effects on pathogenesis and development of acute pancreatitis[1][2].

分子量

448.92

Formula

C20H21ClN4O4S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Patamostat hydrochloride 相关分类

  • 摩尔计算器

  • 稀释计算器

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Patamostat3031765-17-7E-3123E3123E 3123Ser/Thr ProteaseSerine proteasesSerine endopeptidasesThreonine proteasesproteasetrypsinplasminthrombinpathogenesisacutepancreatitisInhibitorinhibitorinhibit

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