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  5. Pulvomycin

Pulvomycin  (Synonyms: Antibiotic 1063Z)

目录号: HY-117730
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摩尔计算器

Pulvomycin (Antibiotic 1063Z)是一种抗生素，具有抑制蛋白质生物合成的活性。Pulvomycin能够阻止在细胞中生长的Bacillus brevis的蛋白质生物合成过程。Pulvomycin在无细胞系统中对多聚（Phe）合成具有高度敏感性。Pulvomycin不影响苯丙氨酸向tRNA的转移。研究表明，Pulvomycin的作用靶点是多肽链的延伸。Pulvomycin还可以预防延伸因子Tu、GTP和氨酰-tRNA之间的三元复合物形成。

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Pulvomycin Chemical Structure

Pulvomycin Chemical Structure

CAS No. : 11006-66-9

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Pulvomycin 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Pulvomycin (Antibiotic 1063Z) is an antibiotic with protein biosynthesis inhibitory activity. Pulvomycin is able to block protein biosynthesis in Bacillus brevis grown in cells. Pulvomycin is highly sensitive to poly(Phe) synthesis in cell-free systems. Pulvomycin does not affect the transfer of phenylalanine to tRNA. Studies have shown that the target of Pulvomycin is the elongation of the polypeptide chain. Pulvomycin can also prevent the formation of a ternary complex between the elongation factor Tu, GTP and aminoacyl-tRNA[1].

分子量

839.02

Formula

C47H66O13
CAS 号
结构分类
初始来源

Streptoverticillium mobaraense
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Pulvomycin 相关分类

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× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pulvomycin11006-66-9Antibiotic 1063ZOthersInhibitorinhibitorinhibit

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