Angiopoietin-1 蛋白, Mouse (HEK293, His, solution)

Angiopoietin-1 (ANGPT1) is a secreted glycoprotein that belongs to the angiopoietin family. It actively regulates blood vessel formation and stabilization, playing a pivotal role in vascular development. ANGPT1 also influences skeletal myoblasts and orchestrates the vascular response to tissue injury. Its broad expression in various tissues highlights its significance in diverse physiological contexts. Angiopoietin-1 Protein, Mouse (HEK293, His, solution) is the recombinant mouse-derived Angiopoietin-1 protein, expressed by HEK293 , with N-His labeled tag.

血管生成素-1 (ANGPT1) 编码血管生长因子血管生成素家族中的一种分泌糖蛋白。作为血管酪氨酸激酶信号通路中的重要配体，该蛋白积极调节血管的形成和稳定，显示出其在血管发育中的关键作用。除了其血管功能外，ANGPT1还在横纹肌中发挥作用，影响骨骼肌母细胞的增殖、迁移和分化。此外，ANGPT1 在协调血管对组织损伤的反应中发挥着至关重要的作用。该基因表现出选择性剪接，导致多种转录变体。它在各种组织中广泛表达，包括心脏、肺和其他解剖部位，强调了 ANGPT1 在不同生理环境中的重要性。

Determined by its ability to induce adhesion of human umbilical vein endothelial cells (HUVEC).The ED₅₀ for this effect is 302.2 ng/mL.

Mouse

HEK293

N-His

NP_033770.2 (R277-F498)

11600  [NCBI]

Approximately 28 kDa

Greater than 95% as determined by reducing SDS-PAGE.

溶液.

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.