1. 重组蛋白
  2. Enzymes & Regulators
  3. Hydrolases (EC 3)
  4. ATL3 蛋白, Human (His)

ATL3 蛋白, Human (His)

目录号: HY-P75497
COA 产品使用指南

ATL3 蛋白是一种 GTP 酶,通过形成反式同聚物来促进膜束缚,从而介导内质网 (ER) 膜的同型融合。ATL3 对于 ER 管状网络生物发生至关重要,有助于这一重要细胞结构的组织和动态。ATL3 蛋白, Human (His) 是重组的 ATL3 蛋白,由 E. coli 表达,带有 N-His 标签。ATL3 蛋白, Human (His) 全长 445 个氨基酸,分子量约为 ~52.6 kDa。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 价格 是否有货 数量
Free Sample   Apply now  
5 μg ¥700 In-stock
10 μg ¥1100 In-stock
50 μg ¥2800 In-stock
100 μg   询价  

* Please select Quantity before adding items.

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

ATL3 protein is a GTPase that mediates homotypic fusion of endoplasmic reticulum (ER) membranes by promoting membrane tethering through the formation of trans homomers. ATL3 is critical for ER tubular network biogenesis, contributing to the organization and dynamics of this important cellular structure. ATL3 Protein, Human (His) is the recombinant human-derived ATL3 protein, expressed by E. coli , with N-His labeled tag. The total length of ATL3 Protein, Human (His) is 445 a.a., with molecular weight of ~52.6 kDa.

研究背景

ATL3 蛋白作为 GTP 酶,通过形成反式同聚体促进膜束缚,从而介导内质网 (ER) 膜的同型融合。这种关键蛋白在内质网内管状网络的生物发生中发挥着至关重要的作用,有助于这种重要细胞结构的组织和动力学。此外,ATL3 与特定蛋白质(例如 ZFYVE27 和 REEP5)相互作用,表明分子关联网络进一步调节其在膜动力学和 ER 结构中的功能作用。

生物活性

Measured by its ability to catalyze the substrate GTP. The specific activity is 613.47 μM/min/μg, as measured under the described conditions.

种属

Human

表达系统

E. coli

标签

N-10*His

蛋白编号

Q6DD88 (M1-A445)

基因 ID
蛋白结构
N-term
His
ATL3 (M1-A445)
Accession # Q6DD88
C-term
同用名
Atlastin-3; ATL3
氨基酸序列

MLSPQRVAAAASRGADDAMESSKPGPVQVVLVQKDQHSFELDEKALASILLQDHIRDLDVVVVSVAGAFRKGKSFILDFMLRYLYSQKESGHSNWLGDPEEPLTGFSWRGGSDPETTGIQIWSEVFTVEKPGGKKVAVVLMDTQGAFDSQSTVKDCATIFALSTMTSSVQIYNLSQNIQEDDLQQLQLFTEYGRLAMDEIFQKPFQTLMFLVRDWSFPYEYSYGLQGGMAFLDKRLQVKEHQHEEIQNVRNHIHSCFSDVTCFLLPHPGLQVATSPDFDGKLKDIAGEFKEQLQALIPYVLNPSKLMEKEINGSKVTCRGLLEYFKAYIKIYQGEDLPHPKSMLQATAEANNLAAAASAKDIYYNNMEEVCGGEKPYLSPDILEEKHCEFKQLALDHFKKTKKMGGKDFSFRYQQELEEEIKELYENFCKHNGSKNVFSTFRTPA

分子量

Approximately 52.6 kDa

纯度
  • Greater than 95% as determined by reducing SDS-PAGE.
性状

无菌粉末

组分

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

保存条件 & 期限

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US; may vary elsewhere.

文件资料

ATL3 Protein, Human (His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
ATL3 Protein, Human (His)
目录号:
HY-P75497
需求量: