CD1D2-B2M Heterodimer 蛋白, Mouse (HEK293, His)

The CD1D2 protein plays a crucial role as an antigen-presenting molecule, binding self and non-self glycolipids and presenting them to T-cell receptors on natural killer T-cells. In partnership with B2M, it mediates immune responses, and its interactions with MHC II and CD74 highlight its significance in the complex network of immune system regulation. CD1D2-B2M Heterodimer Protein, Mouse (HEK293, His) is a recombinant protein dimer complex containing mouse-derived CD1D2-B2M Heterodimer protein, expressed by HEK293 , with C-His labeled tag.

CD1D2-B2M 异二聚体蛋白作为关键的抗原呈递分子，能够结合自身和非自身糖脂，随后将它们呈递给自然杀伤 T 细胞上的 T 细胞受体。在与 B2M（β-2-微球蛋白）的异二聚体伙伴关系中，CD1D2 在介导免疫反应中发挥着至关重要的作用。值得注意的是，它与 MHC II 和 CD74 的相互作用进一步强调了它在复杂的免疫系统调节网络中的重要性。

Immobilized Mouse CD1D2-B2M Heterodimer at 2 μg/mL (100 μL/well) can bind Anti-B2M Antibody. The ED₅₀ for this effect is 0.293 μg/mL.

Mouse

HEK293

C-6*His

P11610 (Q22-G305)&P01887 (I21-M119)

12480  [NCBI]&12010  [NCBI]

Approximately 45-58 & 11-13 kDa.

Greater than 95% as determined by reducing SDS-PAGE

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.