DPP2 蛋白, Human (HEK293, His)

The DPP2 protein is a key member of the dipeptidyl peptidase family and plays a crucial role in the degradation of specific oligopeptides. It hydrolyzes oligopeptide bonds and promotes the breakdown of peptides into amino acids, emphasizing its importance in the regulation of cellular catabolism and peptide metabolism. DPP2 Protein, Human (HEK293, His) is the recombinant human-derived DPP2 protein, expressed by HEK293 , with C-His labeled tag. The total length of DPP2 Protein, Human (HEK293, His) is 471 a.a., with molecular weight of ~60 kDa.

DPP2 蛋白在特定寡肽的降解中发挥着至关重要的作用，有助于参与肽周转的细胞过程。作为二肽基肽酶家族的重要成员，DPP2 参与寡肽键的水解，促进肽分解为其组成氨基酸。这种酶活性强调了其在细胞分解代谢和肽代谢调节中的重要性，说明了其在维持细胞内肽浓度平衡中的关键作用。DPP2 在肽降解中的功能性参与凸显了其在细胞稳态和生物系统内控制肽周转的动态过程中的重要性。

Measured by its ability to cleave the fluorogenic peptide substrate, Lys-Pro-AMC (KP-AMC). Read at excitation and emission wavelengths of 380 nm and 460 nm. The specific activity is 2025.169 pmol/min/µg, as measured under the described conditions.

Human

HEK293

C-His

Q9UHL4 (G22-L492)

29952  [NCBI]

GARRAPDPGFQERFFQQRLDHFNFERFGNKTFPQRFLVSDRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQSTQRGHTELLTVEQALADFAELLRALRRDLGAQDAPAIAFGGSYGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPKCTQGVREAFRQIKDLFLQGAYDTVRWEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRLLSEAQRITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFASNNVTDMFPDLPFTDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPWAGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWVKAARREQQPALRGGPRLSL

Approximately 60 kDa

• 
  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.