EDAR 蛋白, Human (HEK293, Fc)

EDAR Protein, a receptor for EDA isoform A1, activates NF-kappa-B and JNK signaling pathways upon binding, eliciting diverse cellular responses. It may also contribute to caspase-independent cell death. EDAR forms a complex with EDARADD and associates with signaling molecules like TRAF1, TRAF2, TRAF3, and NIK, highlighting its participation in intricate signaling cascades. EDAR Protein, Human (HEK293, Fc) is the recombinant human-derived EDAR protein, expressed by HEK293 , with C-hFc labeled tag.

EDAR 是专门针对 EDA 同工型 A1 的受体，使其与 EDA 同工型 A2 区别开来。结合后，EDAR 促进 NF-kappa-B 和 JNK 信号通路的激活，可能导致各种细胞反应。此外，EDAR 可能在促进不依赖 caspase 的细胞死亡中发挥作用。该受体与 EDARADD 形成复合物，并与 TRAF1、TRAF2、TRAF3 和 NIK 等关键信号分子相关，表明其参与复杂的信号级联反应。

Human

HEK293

C-hFc

Q9UNE0-1 (E27-I189)

10913  [NCBI]

Approximately 52 kDa

Greater than 95% as determined by reducing SDS-PAGE

溶液

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.