1. 重组蛋白
  2. Cytokines and Growth Factors CD Antigens
  3. CSF & Receptors Macrophage CD Proteins Monocyte CD Proteins Endothelial cell CD Proteins
  4. GM-CSFR GM-CSF R alpha/CD116
  5. GM-CSF R alpha/CD116
  6. GM-CSF R alpha 蛋白, Cynomolgus (HEK293, His)

GM-CSF R alpha 蛋白, Cynomolgus (HEK293, His)

目录号: HY-P700730
产品使用指南

GM-CSF Rα蛋白是5型亚家族中重要的I型细胞因子受体,在介导细胞对多种细胞因子的反应中发挥重要作用。它与转导来自特定 I 型细胞因子的信号的相关受体具有保守的特征,强调了其在更广泛的细胞信号传导背景下对造血和免疫调节的独特贡献。GM-CSF R alpha 蛋白, Cynomolgus (298.a.a, HEK293, His) 是重组的 GM-CSF R α 蛋白,由 HEK293 表达,带有 C-His 标签。

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SPR 检测服务   重组蛋白定制服务

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     可免费申领三个不同产品的试用装。

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描述

GM-CSF R α protein is an important type I cytokine receptor in the type 5 subfamily and plays an important role in mediating cellular responses to various cytokines. It shares conserved features with related receptors that transduce signals from specific type I cytokines, emphasizing its unique contribution to hematopoiesis and immune regulation in the broader context of cell signaling. GM-CSF R alpha Protein, Cynomolgus (298.a.a, HEK293, His) is the recombinant cynomolgus-derived GM-CSF R alpha protein, expressed by HEK293 , with C-His labeled tag.

研究背景

GM-CSF R α 蛋白是 I 型细胞因子受体家族的重要成员,特别归类于 5 型亚家族,突出了其在介导细胞对各种细胞因子的反应中的重要作用。作为该受体家族的一部分,GM-CSF R α 可能与相关受体具有保守的结构和功能特征,强调其参与转导来自特定 I 型细胞因子的信号。I 型细胞因子受体家族的分类强调了其在更广泛的细胞信号传导背景下的特定名称,从而深入了解其对造血和免疫调节的独特贡献。GM-CSF R α 的研究有助于我们了解其在生理过程中的作用,为造血障碍和免疫失调相关疾病的治疗干预提供了潜在的应用。对 GM-CSF R α 作用的进一步探索有望增强我们对其对正常细胞功能和病理状况的贡献的了解。

种属

Cynomolgus

表达系统

HEK293

标签

C-His

蛋白编号

A0A2K5UC70 (L20-S317)

基因 ID

/

蛋白结构
N-term
GM-CSF?R?alpha (L20-S317)
Accession # A0A2K5UC70
His
C-term
同用名
GM-CSF-R-alpha; GMCSFR-alpha; GMR-alpha; CSF2R; CSF2RY; CSF2RA; CDw116; CD116; CSF2RAX; CSF2RAY; CSF2RX; GMCSFR; GMR; SMDP4
分子量

60-70 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
GM-CSF R alpha Protein, Cynomolgus (HEK293, His)
目录号:
HY-P700730
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