Histo-blood group ABO/ABO 蛋白, Human (HEK293, Fc)

The Histo-blood group ABO/ABO Protein is an enzyme encoded by the human ABO gene with glycosyltransferase activity. ABO Protein is associated with a variety of infectious and non-communicable diseases. ABO blood group can be used as a tumor marker. Histo-blood group ABO/ABO Protein, Human (HEK293, Fc) is the recombinant human-derived Histo-blood group ABO/ABO protein, expressed by HEK293 , with N-hFc labeled tag. The total length of Histo-blood group ABO/ABO Protein, Human (HEK293, Fc) is 292 a.a., with molecular weight of ~62-68 kDa.

组织血型 ABO 系统转移酶是人类 ABO 基因编码的一种具有糖基转移酶活性的酶。它在许多组织和细胞类型中普遍表达。ABO 通过修饰细胞表面糖蛋白上的寡糖来确定个体的 ABO 血型。个体之间蛋白质序列的差异决定了修饰的类型和血型。ABO 基因还包含与冠状动脉疾病风险增加相关的 27 个 SNP 中的一个。基因决定的人类 ABO 血型与各种传染性和非传染性疾病的风险增加相应相关。ABO 血型可作为肿瘤标记物。

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Human

HEK293

N-hFc

ADX99264 (R63-P354)

28  [NCBI]

RVSLPRMVYPQPKVLTPCRKDVLVVTPWLAPIVWEGTFNIDILNEQFRLQNTTIGLTVFAIKKYVAFLKLFLETAEKHFMVGHRVHYYVFTDQPAAVPRVTLGTGRQLSVLEVGAYKRWQDVSMRRMEMISDFCERRFLSEVDYLVCVDVDMEFRDHVGVEILTPLFGTLHPSFYGSSREAFTYERRPQSQAYIPKDEGDFYYMGAFFGGSVQEVQRLTRACHQAMMVDQANGIEAVWHDESHLNKYLLRHKPTKVLSPEYLWDQQLLGWPAVLRKLRFTAVPKNHQAVRNP

Approximately 62-68 kDa

• 
  Greater than 90% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in PBS. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.