1. 重组蛋白
  2. CD Antigens Receptor Proteins
  3. NK Cell CD Proteins Macrophage CD Proteins Monocyte CD Proteins Dendritic Cell CD Proteins Leukocyte Immunoglobin-like Receptors
  4. CD85j/LIR-1
  5. LILRB1/CD85j/ILT2 蛋白, Rhesus macaque (440a.a, HEK293, Fc)

LILRB1/CD85j/ILT2 蛋白, Rhesus macaque (440a.a, HEK293, Fc)

目录号: HY-P78325
产品使用指南

LILRB1/CD85j/ILT2 蛋白是一种在白细胞上广泛表达的抑制性受体,可识别 HLA I 类和人巨细胞病毒 UL18。LILRB1/CD85j/ILT2 蛋白, Rhesus macaque (440a.a, HEK293, Fc) 是重组的 LILRB1/CD85j/ILT2 蛋白,由 HEK293 表达,带有 C-hFc 标签。LILRB1/CD85j/ILT2 蛋白, Rhesus macaque (440a.a, HEK293, Fc) 全长 440 个氨基酸,分子量为 80-90 kDa。

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描述

LILRB1/CD85j/ILT2 Protein is an inhibitory receptor broadly expressed on leukocytes and recognizes HLA-class I and human cytomegalovirus UL18[1]. LILRB1/CD85j/ILT2 Protein, Rhesus macaque (440a.a, HEK293, Fc) is the recombinant Rhesus Macaque-derived LILRB1/CD85j/ILT2 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of LILRB1/CD85j/ILT2 Protein, Rhesus macaque (440a.a, HEK293, Fc) is 440 a.a., with molecular weight of 80-90 kDa.

研究背景

LILRB1/CD85j/ILT2 蛋白是白细胞免疫球蛋白样受体 (LIR) 家族的成员,包含两个或四个细胞外免疫球蛋白结构域、一个跨膜结构域和两到四个基于细胞质免疫受体酪氨酸的抑制基序 (ITIM)[3]。LILRB1/CD85j/ILT2 蛋白在免疫细胞上表达,与抗原呈递细胞上的 MHC I 类分子结合,并转导抑制免疫反应刺激的负信号。它被认为可以控制炎症反应和细胞毒性,以帮助集中免疫反应并限制自身反应[4]

种属

Rhesus Macaque

表达系统

HEK293

标签

C-hFc

蛋白编号

F7H3G7 (S17-H456)

基因 ID
蛋白结构
N-term
LILRB1 (S17-H456)
Accession # F7H3G7
hFc
C-term
同用名
ILT2; ILT-2; ILT2FLJ37515; LILRB1; LIR1; MIR7; CD85J; XXbac-BCX85G21.4
分子量

80-90 kDa

纯度

Greater than 95% as determined by Tris-Bis PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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  • 重组蛋白稀释计算器

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
LILRB1/CD85j/ILT2 Protein, Rhesus macaque (440a.a, HEK293, Fc)
目录号:
HY-P78325
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