1. 重组蛋白
  2. Receptor Proteins
  3. NKp46/NCR1 蛋白, Cynomolgus (HEK293, His)

NKp46/NCR1 蛋白, Cynomolgus (HEK293, His)

目录号: HY-P78007
COA 产品使用指南

NKp46/NCR1 蛋白是一种关键的细胞毒性激活受体,可提高激活的自然杀伤 (NK) 细胞破坏肿瘤细胞的效率。它与 CD3Z 和 FCER1G 相互作用,有可能增强 NK 细胞识别和癌细胞的靶向裂解。NKp46/NCR1 蛋白, Cynomolgus (HEK293, His) 是重组的 NKp46/NCR1 蛋白,由 HEK293 表达,带有 C-His 标签。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

SPR 检测服务   重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 价格 是否有货 数量
20 μg ¥1300 In-stock
50 μg ¥2500 In-stock
100 μg ¥4000 In-stock
> 100 μg   询价  

* Please select Quantity before adding items.

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

NKp46/NCR1 Protein, a pivotal cytotoxicity-activating receptor, enhances the efficiency of activated natural killer (NK) cells in destroying tumor cells. It interacts with CD3Z and FCER1G, potentially amplifying NK cell recognition and targeted lysis of cancerous cells. NKp46/NCR1 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived NKp46/NCR1 protein, expressed by HEK293 , with C-His labeled tag.

研究背景

NKp46/NCR1 蛋白是一种细胞受体,在增强激活的自然杀伤 (NK) 细胞破坏肿瘤细胞的效率方面发挥着至关重要的作用。它作为细胞毒性激活受体,可能有助于 NK 细胞裂解肿瘤细胞的过程。NKp46/NCR1 蛋白与 CD3Z 和 FCER1G 相互作用,可能进一步增强 NK 细胞识别和靶向癌细胞的能力。

生物活性

Immobilized Cynomolgus NKp46, His Tag at 0.5 μg/mL (100 μl/Well) on the plate. Dose response curve for Anti-NKp46 Antibody, hFc Tag with the EC50 of ≤7.0 ng/mL determined by ELISA.

种属

Cynomolgus

表达系统

HEK293

标签

C-His

蛋白编号

Q95JB9 (P22-N254)

基因 ID
蛋白结构
N-term
NKp46 (P22-N254)
Accession # Q95JB9
His
C-term
同用名
CD335; Ly94; NCR1; NKp46; MAR-1; NKP46FLJ99094
分子量

35-45 kDa

纯度

Greater than 95% as determined by Tris-Bis PAGE.

性状

无菌粉末

组分

Lyophilized from 0.22 μm filtered solution in 20 mM Tris, 150 mM NaCl, 100 mM L-arginine, pH 8.2 or PBS, pH 7.4. Normally 8% trehalose is added as protectant before lyophilization.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.

保存条件 & 期限

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US; may vary elsewhere.

文件资料

NKp46/NCR1 Protein, Cynomolgus (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
NKp46/NCR1 Protein, Cynomolgus (HEK293, His)
目录号:
HY-P78007
需求量: