1. 重组蛋白
  2. Receptor Proteins
  3. Prolactin R 蛋白, Cynomolgus (HEK293, His)

Prolactin R 蛋白, Cynomolgus (HEK293, His)

目录号: HY-P700814
COA 产品使用指南

催乳素 R 蛋白是催乳素的受体,可促进多种分子相互作用,例如与 SMARCA1 的关联,表明可能参与染色质重塑。它与 NEK3 和 VAV2 的催乳素依赖性相互作用表明这种相互作用可以调节对刺激的反应。Prolactin R 蛋白, Cynomolgus (HEK293, His) 是重组的 催乳素 R 蛋白,由 HEK293 表达,带有 C-His 标签。Prolactin R 蛋白, Cynomolgus (HEK293, His) 全长 212 个氨基酸,分子量为 35-50 kDa。

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规格 价格 是否有货 数量
20 μg ¥1800 In-stock
50 μg ¥3400 In-stock
100 μg ¥5500 询价
> 100 μg   询价  

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  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

The prolactin R protein is a receptor for prolactin that promotes multiple molecular interactions, such as association with SMARCA1, suggesting a possible involvement in chromatin remodeling. Its prolactin-dependent interaction with NEK3 and VAV2 suggests interactions that regulate responses to stimuli. Prolactin R Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Prolactin R protein, expressed by HEK293 , with C-His labeled tag. The total length of Prolactin R Protein, Cynomolgus (HEK293, His) is 212 a.a., with molecular weight of 35-50 kDa.

研究背景

催乳素 R 蛋白作为专门为垂体前叶激素催乳素设计的受体发挥作用。该受体促进细胞对催乳素的反应,参与多种分子相互作用,包括与 SMARCA1 的关联,表明可能参与染色质重塑过程。此外,催乳素 R 蛋白以催乳素依赖性方式与 NEK3 和 VAV2 相互作用,表明对催乳素刺激的反应受到调节的相互作用。这些相互作用强调了受体在转导催乳素介导的信号、影响细胞过程以及有助于调节多种生理功能方面的关键作用。

生物活性

Immobilized Cynomolgus PRLR, His Tag at 5 μg/mL (100 μl/well) on the plate. Dose response curve for Anti-PRLR Antibody, hFc Tag with the EC50 of ≤35 ng/mL determined by ELISA.

种属

Cynomolgus

表达系统

HEK293

标签

C-His

蛋白编号

A0A2K5WXK1 (Q25-T236)

基因 ID

102139140

蛋白结构
N-term
Prolactin R (Q25-T236)
Accession # A0A2K5WXK1
His
C-term
同用名
PRL-R; HPRL; MFAB; Prolactin R
分子量

35-50 kDa, due to glycosylation

纯度

Greater than 95% as determined by reducing SDS-PAGE.

性状

无菌粉末

组分

Lyophilized from a 0.22 μm filtered solution of 50mM Tris, 150mM NaCl, pH 7.5. Normally 8% trehalose is added as protectant before lyophilization.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.

保存条件 & 期限

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US; may vary elsewhere.

文件资料

Prolactin R Protein, Cynomolgus (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
Prolactin R Protein, Cynomolgus (HEK293, His)
目录号:
HY-P700814
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