2. 重组蛋白
  3. STAT6 蛋白, Human (sf9, His, Strep)

STAT6 蛋白, Human (sf9, His, Strep)

目录号: HY-P703579
COA 产品使用指南

STAT6是一种多功能蛋白，具有信号转导和转录激活的双重功能。它在介导 IL4/interleukin-4 和 IL3/interleukin-3 诱导的信号级联中发挥着至关重要的作用。STAT6 蛋白, Human (sf9, His, Strep) 是重组的 STAT6 蛋白，由 Sf9 insect cells 表达，带有 C-His; C-Strep labeled 标签。

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规格 价格 是否有货 数量
10 μg ￥2250 In-stock
50 μg ￥5800 In-stock
100 μg   询价  

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描述

STAT6 is a multifunctional protein that performs dual functions of signal transduction and transcriptional activation. It plays a crucial role in mediating IL4/interleukin-4 and IL3/interleukin-3 induced signaling cascades. STAT6 Protein, Human (sf9, His, Strep) is the recombinant human-derived STAT6 protein, expressed by Sf9 insect cells , with C-His; C-Strep labeled tag.
研究背景

STAT6（信号转导和转录激活剂6）是一种多功能蛋白，在信号转导和转录激活中发挥双重作用。它特别参与介导白细胞介素 4 (IL-4) 和白细胞介素 3 (IL-3) 触发的信号传导通路。STAT6可以与相关家族成员形成同二聚体或异二聚体，促进其参与各种细胞过程。此外，STAT6 通过其 C 端 LXXLL 基序与核受体共激活剂 NCOA1 相互作用，表明其在调节基因表达方面具有潜在作用。这种相互作用进一步强调了 STAT6 参与转录调控，突出了它在协调细胞通路中的信号事件和转录反应方面的多功能性。
种属

Human
表达系统

Sf9 insect cells
标签

C-His;C-Strep
蛋白编号

P42226 (M1-W847)
基因 ID

6778
蛋白结构
N-term
STAT6 (M1-W847)
Accession # P42226
His-Strep
C-term
同用名
Signal Transducer and Activator of Transcription 6; IL-4 Stat; STAT6
分子量

Approximately 97.1 KDa
纯度

Greater than 90% as determined by reducing SDS-PAGE.
性状

溶液.
组分

Supplied as a 0.2 μm filtered solution of 50 mM HEPES, pH7.5, 200 mM NaCl, 20% glycerol, 1 mM DTT.
内毒素含量

<1 EU/μg, determined by LAL method.
复溶方法

Please use rapid thawing with running water to thaw the protein.
保存条件 & 期限

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
运输条件

Shipping with dry ice.
文件资料

COA (209 KB)

产品使用指南 (1213 KB)
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称：
STAT6 Protein, Human (sf9, His, Strep)
目录号：
HY-P703579
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