TPPP3 蛋白, Human (His)

TPPP3 Protein, a microtubule-associated regulator, crucially influences microtubule dynamics through bundling activity. Its essential role extends to embryo implantation and decidualization, implicating reproductive events. The impact on implantation suggests a regulatory function linked to beta-catenin, a key signaling molecule. TPPP3's involvement in decidualization emphasizes its significance in cellular events, particularly through beta-catenin signaling, making TPPP3 a versatile player in cellular dynamics with implications for development and reproduction. TPPP3 Protein, Human (His) is the recombinant human-derived TPPP3 protein, expressed by E. coli, with N-His labeled tag. The total length of TPPP3 Protein, Human (His) is 176 a.a., with molecular weight of ~21 kDa.

TPPP3 是一种微管相关蛋白，作为微管动力学的调节者发挥着关键作用，通过微管成束活性发挥其影响。它的重要参与延伸到关键的生物过程，特别是胚胎植入和蜕膜化，表明在生殖事件中发挥作用。对胚胎植入的影响意味着与β-连环蛋白（细胞过程中的关键信号分子）相关的潜在调节功能。此外，TPPP3 在蜕膜化中的作用增强了其在协调细胞事件中的重要性，特别是通过其对 β-连环蛋白信号传导的影响。这些发现强调了 TPPP3 作为细胞动力学中的多功能参与者，对发育和繁殖的基本过程具有影响。

Human

E. coli

N-His

Q9BW30 (M1-K176)

51673  [NCBI]

MAASTDMAGLEESFRKFAIHGDPKASGQEMNGKNWAKLCKDCKVADGKSVTGTDVDIVFSKVKGKSARVINYEEFKKALEELATKRFKGKSKEEAFDAICQLVAGKEPANVGVTKAKTGGAVDRLTDTSRYTGSHKERFDESGKGKGIAGRQDILDDSGYVSAYKNAGTYDAKVKK

Approximately 19 kDa

Greater than 95% as determined by reducing SDS-PAGE

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.