2. Epigenetics
  3. Histone Acetyltransferase
  4. SPV106

SPV106 是组蛋白乙酰化酶 (HAT) 和 GCN5 相关的 N-乙酰转移酶 (GNAT) 激活剂。 SPV106 可用于 2 型糖尿病 (T2D) 的研究。

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SPV106 Chemical Structure

SPV106 Chemical Structure

CAS No. : 1036939-38-4

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SPV106 相关抗体

Top Publications Citing Use of Products

查看 Histone Acetyltransferase 亚型特异性产品:

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CBP/p300 GCN5/PCAF TIP60 MOZ/MORF HBO1

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SPV106 is histone acetylase (HAT) and GCN5-related N-acetyltransferases (GNAT) activator. SPV106 can be used for the research of type 2 diabetes (T2D)[1].

体外研究
(In Vitro)

SPV106 恢复正常水平的 H3K9Ac 和 H3K14Ac，降低 DNA CpG 高甲基化，恢复 D-CMSC 增殖和分化[1]。
SPV106 (5 µmol/L) 在 D-CMSC[1] 中减少细胞衰老并诱导 cKit 表达[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

SPV106 相关抗体:

Western Blot Analysis[1]

Cell Line: Human cardiac-specific mesenchymal cell (CMSC)
Concentration: 25 μmol/L
Incubation Time: 6-8 days
Result: Achieved partial but significant rescue of HAT activity.

RT-PCR[1]

Cell Line: Human cardiac-specific mesenchymal cell (CMSC)
Concentration: 25 μmol/L
Incubation Time: 7 days
Result: Not associated to a rescue in gene transcription.
分子量

368.55

Formula

C22H40O4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

SPV106 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SPV1061036939-38-4SPV 106SPV-106Histone AcetyltransferaseHATsHAThistone acetylase (HAT)GCN5-related N-acetyltransferases (GNAT)type 2 diabetes (T2D)Inhibitorinhibitorinhibit

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产品名称：
SPV106
目录号：
HY-114566
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