2. Cell Cycle/DNA Damage Cytoskeleton
  3. Microtubule/Tubulin
  4. Tubulin inhibitor 16

Tubulin inhibitor 16 是一种有效的 tubulin 抑制剂。Tubulin inhibitor 16 显示出抗增殖活性。Tubulin inhibitor 16 在 HepG2 细胞中显示出细胞毒性。

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Tubulin inhibitor 16 Chemical Structure

Tubulin inhibitor 16 Chemical Structure

CAS No. : 2767446-32-0

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Tubulin inhibitor 16 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Tubulin inhibitor 16 is a potent tubulin inhibitor. Tubulin inhibitor 16 shows antiproliferative activity. Tubulin inhibitor 16 shows cytotoxicity in HepG2 cells[1].

体外研究
(In Vitro)

Tubulin inhibitor 16 (compound 2) (0-25 µM, 24 h followed by a 72 h compound-free incubation period) shows antiproliferative activity with IC50s of 1.43, 0.19, 2.33, 0.58, 0.83, 0.20, >25 µM for MCF7, MDA-MB-231, HepG2, SNU423, A549, HCT116, THLE-3 cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Tubulin inhibitor 16 相关抗体:

Cell Proliferation Assay[1]

Cell Line: MCF7, MDA-MB-231, HepG2, SNU423, A549, HCT116 cells
Concentration: 0-50 µM
Incubation Time: 96 h
Result: Showed antiproliferation activity with IC50s of 0.75, 0.17, 3.12, 0.41, 0.37, 0.22 µM for MCF7, MDA-MB-231, HepG2, SNU423, A549, HCT116 cells, respectively.

Cell Cytotoxicity Assay[1]

Cell Line: HepG2 cells
Concentration: 0.5, 1 µM
Incubation Time: 14 days
Result: Showed no colonies were apparent when cells were treated with 0.5 or 1 µM.
分子量

269.27

Formula

C16H12FNO2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Tubulin inhibitor 16 相关分类

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tubulin inhibitor 162767446-32-0Tubulin inhibitor16Tubulin inhibitor-16Microtubule/TubulinAntiproliferativecytotoxicityHepG2 cellsTHLE-3 cellsInhibitorinhibitorinhibit

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