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  4. 2-Deoxy-D-galactose

2-Deoxy-D-galactose 是葡萄糖的类似物。2-Deoxy-D-galactose 通过抑制糖酵解来抑制肿瘤生长。2-Deoxy-D-galactose 是一种干扰糖大分子聚焦化的物质，在各种学习任务中损害记忆巩固。2-Deoxy-D-galactose 阻碍体内糖蛋白集中化。

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2-Deoxy-D-galactose Chemical Structure

2-Deoxy-D-galactose Chemical Structure

CAS No. : 1949-89-9

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2-Deoxy-D-galactose 相关抗体

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MCE 顾客使用本产品发表的 1 篇科研文献

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

2-Deoxy-D-galactose is a glucose analog. 2-Deoxy-D-galactose inhibits glycolysis to inhibits tumor growth. 2-Deoxy-D-galactose is a substance interfering with the fucosylation of glycomacromolecules and impairing memory consolidation in various learning tasks. 2-Deoxy-d-galactose hinders glycoprotein fucosylation in vivo[1].

体外研究
(In Vitro)

2-Deoxy-D-galactose (1 mM/L; 5 h) is rapid phosphorylation during the first 30 min and decreases to approximately 20% of this rate during the subsequent hours in ascites hepatoma cells[4].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

2-Deoxy-D-galactose 相关抗体:
体内研究
(In Vivo)

2-Deoxy-D-galactose (380 mg/kg; i.p.; for 6 times) strongly decreases contents of UMP, UDPG, and UDP galactose in rat livers[1].
2-Deoxy-D-galactose (2-8 μM; intracerebroventricularly injection; once) shows PAR impairment 30 min before the acquisition trial a dose of 4 μM and 15 min delay after do-gal administration[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male adult Wistar rats with passive avoidance response (PAR) acquisition trial[3]
Dosage: 2, 4 and 8 μM
Administration: Intracerebroventricularly injection; 2-8 μM; once
Result: Exhibited PAR disruption at a dose of 4 μM.
分子量

164.16

Formula

C6H12O5
CAS 号
性状

固体

颜色

Off-white to light yellow

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶解性数据
细胞实验： 

H2O 中的溶解度 : 250 mg/mL (1522.90 mM; 超声助溶)

Methanol 中的溶解度 : 125 mg/mL (761.45 mM; 超声助溶)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 6.0916 mL 30.4581 mL 60.9162 mL
5 mM 1.2183 mL 6.0916 mL 12.1832 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

* 备注：如您选择水作为储备液，请稀释至工作液后，再用 0.22 μm 的滤膜过滤除菌后使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
该产品水溶性佳，请具体参考实测 水 / PBS / Saline 中的溶解度数据。
您所需的储备液浓度超过该产品的实测溶解度，如有需要，请与 MCE 中国技术支持联系。
纯度 & 产品资料
参考文献

2-Deoxy-D-galactose 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
Methanol / H2O 1 mM 6.0916 mL 30.4581 mL 60.9162 mL 152.2904 mL
5 mM 1.2183 mL 6.0916 mL 12.1832 mL 30.4581 mL
10 mM 0.6092 mL 3.0458 mL 6.0916 mL 15.2290 mL
15 mM 0.4061 mL 2.0305 mL 4.0611 mL 10.1527 mL
20 mM 0.3046 mL 1.5229 mL 3.0458 mL 7.6145 mL
25 mM 0.2437 mL 1.2183 mL 2.4366 mL 6.0916 mL
30 mM 0.2031 mL 1.0153 mL 2.0305 mL 5.0763 mL
40 mM 0.1523 mL 0.7615 mL 1.5229 mL 3.8073 mL
50 mM 0.1218 mL 0.6092 mL 1.2183 mL 3.0458 mL
60 mM 0.1015 mL 0.5076 mL 1.0153 mL 2.5382 mL
80 mM 0.0761 mL 0.3807 mL 0.7615 mL 1.9036 mL
100 mM 0.0609 mL 0.3046 mL 0.6092 mL 1.5229 mL

* 备注：如您选择水作为储备液，请稀释至工作液后，再用 0.22 μm 的滤膜过滤除菌后使用。

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2-Deoxy-D-galactose1949-89-9Othersglycolysisphosphateuridylatephosphorylationascites hepatomapassive avoidance responseUMPUDPGInhibitorinhibitorinhibit

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