2. 天然产物
  3. 疾病研究领域 植物 醌类
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  5. 睡茄
  6. 4-Dehydrowithaferin A

4-Dehydrowithaferin A  (Synonyms: 4-oxo Withaferin A)

目录号: HY-138146
产品使用指南

摩尔计算器

4-Dehydrowithaferin A 是withaferin A 的类似物。Withaferin A 是一种从Withania somnifera 中分离出来的 withaferin A。4-Dehydrowithaferin A 具有研究多发性骨髓瘤的潜力。

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4-Dehydrowithaferin A Chemical Structure

4-Dehydrowithaferin A Chemical Structure

CAS No. : 6850-30-2

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规格 价格 是否有货 数量
1 mg ￥1836
3 - 4 周
5 mg   询价  
10 mg   询价  

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4-Dehydrowithaferin A 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

4-Dehydrowithaferin A is the analogue of withaferin A. Withaferin A is a withanolide isolated from Withania somnifera. 4-Dehydrowithaferin A has the potential for the research of multiple myeloma[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A2780 IC50
7.3 nM
Compound: 23
Antiproliferative activity against cisplatin-sensitive human A2780 cells measured after 96 hrs by MTT assay
Antiproliferative activity against cisplatin-sensitive human A2780 cells measured after 96 hrs by MTT assay
[PMID: 31008605]
A549 IC50
12.8 μM
Compound: 15
Cytotoxicity against human A549 cells assessed as cell viability after 72 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as cell viability after 72 hrs by MTT assay
[PMID: 22705001]
A549 IC50
25.4 μM
Compound: 15
Cytotoxicity against human A549 cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 22705001]
ARPE-19 IC50
32 nM
Compound: 23
Cytotoxicity against human ARPE19 cells measured after 96 hrs by MTT assay
Cytotoxicity against human ARPE19 cells measured after 96 hrs by MTT assay
[PMID: 31008605]
HeLa IC50
15.2 μM
Compound: 15
Cytotoxicity against human HeLa cells assessed as cell viability after 72 hrs by MTT assay
Cytotoxicity against human HeLa cells assessed as cell viability after 72 hrs by MTT assay
[PMID: 22705001]
HeLa IC50
18.4 μM
Compound: 15
Cytotoxicity against human HeLa cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity against human HeLa cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 22705001]
MCF7 IC50
2.1 μM
Compound: 15
Cytotoxicity against human MCF7 cells assessed as cell viability after 72 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as cell viability after 72 hrs by MTT assay
[PMID: 22705001]
MCF7 IC50
3.2 μM
Compound: 15
Cytotoxicity against human MCF7 cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 22705001]
NCI-H929 IC50
1.16 μM
Compound: 27
Cytotoxicity against human NCI-H929 cells after 3 days by Alamar blue assay
Cytotoxicity against human NCI-H929 cells after 3 days by Alamar blue assay
[PMID: 24625088]
Vero IC50
1.5 μM
Compound: 15
Cytotoxicity against african green monkey Vero cells assessed as cell viability after 72 hrs by MTT assay
Cytotoxicity against african green monkey Vero cells assessed as cell viability after 72 hrs by MTT assay
[PMID: 22705001]
Vero IC50
7.7 μM
Compound: 15
Cytotoxicity against african green monkey Vero cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity against african green monkey Vero cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 22705001]
分子量

468.58

Formula

C28H36O6
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

4-Dehydrowithaferin A 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

4-Dehydrowithaferin A6850-30-24-oxo Withaferin AOtherswithaferin AwithanolideWithania somniferamultiple myelomaInhibitorinhibitorinhibit

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