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  4. 5-Fluoroorotic acid monohydrate

5-Fluoroorotic acid monohydrate  (Synonyms: 5-Fluorouracil-6-carboxylic acid Mono(hydrate); 5-FOA; 5-fluoro OA)

目录号: HY-W016819B
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5-Fluoroorotic acid (monohydrate) (5-Fluorouracil-6-carboxylic acid Mono(hydrate); 5-FOA) 用于检测酵母分子遗传构建体中的 URA3 基因表达。具有活性 URA3 基因的酵母（该基因编码乳清酸苷-5'-单磷酸脱羧酶）将 5-FOA 转化为氟脱氧尿苷，后者对细胞有毒性。如果培养基中添加了尿嘧啶，携带 URA3 基因突变的抗性酵母菌株会在 5-FOA 存在下生长。

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5-Fluoroorotic acid monohydrate Chemical Structure

5-Fluoroorotic acid monohydrate Chemical Structure

CAS No. : 220141-70-8

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5-Fluoroorotic acid monohydrate 相关抗体

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生物活性

5-Fluoroorotic acid (monohydrate) (5-Fluorouracil-6-carboxylic acid Mono(hydrate); 5-FOA) is used to detect URA3 gene expression in yeast molecular genetic constructs. Yeast with an active URA3 gene (which encodes orotidine-5'-monophosphate decarboxylase) convert 5-FOA to fluorodeoxyuridine, which is toxic to cells. Resistant yeast strains carrying mutations in the URA3 gene will grow in the presence of 5-FOA if uracil is added to the culture medium.

分子量

192.10

Formula

C5H5FN2O5
CAS 号
性状

固体

颜色

White to light yellow

中文名称

5-氟乳清酸 一水合物
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

纯度 & 产品资料
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5-Fluoroorotic acid monohydrate 相关分类

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Keywords:

5-Fluoroorotic acid220141-70-85-Fluorouracil-6-carboxylic acid Mono(hydrate) 5-FOA 5-fluoro OA5-氟乳清酸 一水合物OthersInhibitorinhibitorinhibit

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