2. Apoptosis
  3. Apoptosis
  4. 7-Ketositosterol

7-Ketositosterol 是一种植物甾醇，能从桑树 (Morus alba L.) 果实中分离得到。7-Ketositosterol 可显著抑制 Cisplatin (HY-17394) 诱导的 LLC-PK1 细胞凋亡 (apoptosis)，具有改善 Cisplatin 诱导的肾毒性的潜力。

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7-Ketositosterol Chemical Structure

7-Ketositosterol Chemical Structure

CAS No. : 2034-74-4

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7-Ketositosterol 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

7-Ketositosterol is a phytosterol isolated from the fruits of the mulberry tree (Morus alba L.). 7-Ketositosterol can significantly inhibit Cisplatin (HY-17394)-induced apoptosis in LLC-PK1 cells and has the potential to improve Cisplatin-induced nephrotoxicity[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
BV-2 IC50
> 100 μM
Compound: 36
Antineuroinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced NO production after 24 hrs in presence of LPS by Griess reaction based assay
Antineuroinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced NO production after 24 hrs in presence of LPS by Griess reaction based assay
[PMID: 28911817]
HT-29 IC50
48 μM
Compound: 29
Cytotoxicity against human HT-29 cells after 48 hrs by Alamar blue assay
Cytotoxicity against human HT-29 cells after 48 hrs by Alamar blue assay
[PMID: 20931970]
分子量

428.69

Formula

C29H48O2
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

7-Ketositosterol 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

7-Ketositosterol2034-74-4ApoptosisLLC-PK1MAPKsMorus albamulberrynephrotoxicityphytosterolsInhibitorinhibitorinhibit

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目录号：
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