1. Metabolic Enzyme/Protease
  2. Angiotensin-converting Enzyme (ACE)
  3. H-Ile-Pro-Pro-OH

H-Ile-Pro-Pro-OH 是一种乳源三肽,抑制血管紧张素转换酶 (ACE) ,IC50 为 5 μM。具有抗高血压效果。

在相同的摩尔浓度下,化合物盐形式与游离形式有相同的生物活性,但盐形式 H-Ile-Pro-Pro-OH hydrochloride 通常具有更好的水溶性和稳定性。

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Custom Peptide Synthesis

H-Ile-Pro-Pro-OH Chemical Structure

H-Ile-Pro-Pro-OH Chemical Structure

CAS No. : 26001-32-1

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规格 是否有货
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100 mg   询价  
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H-Ile-Pro-Pro-OH 的其他形式现货产品:

Customer Review

Other Forms of H-Ile-Pro-Pro-OH:

MCE 顾客使用本产品发表的 1 篇科研文献

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

H-Ile-Pro-Pro-OH, a milk-derived peptide[1], inhibits angiotensin-converting enzyme (ACE)[1] with an IC50 of 5 μM[2]. Antihypertensive tripeptides[1].

IC50 & Target

IC50: 5 μM (ACE)[2]

体外研究
(In Vitro)

Ile-Pro-Pro (IPP; 1 nM, 0.1 μM, and 10 μM) increases nitric oxide (NO) production in human umbilical vein endothelial cells (HUVECs)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Ile-Pro-Pro (IPP; 30 mg/kg per day; 0.3 g/L) attenuates arterial dysfunction in L-NAME-treated rats[1]
Ile-Pro-Pro decreases blood pressure in spontaneously hypertensive rats (SHR) [1].
Ile-Pro-Pro attenuates the development of atherosclerosis in apolipoprotein E-deficient (apoE(-/-)) mice[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

325.40

Formula

C16H27N3O4

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
H-Ile-Pro-Pro-OH
目录号:
HY-114424
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