2. Immunology/Inflammation NF-κB Metabolic Enzyme/Protease
  3. Reactive Oxygen Species
  4. Hydralazine

Hydralazine 是一种具有口服活性的降压药，通过放松动脉血管平滑肌细胞层，直接降低外周阻力。Hydralazine 具有抗氧化活性，抑制活性氧 (ROS) 释放和 O2·- 生成，IC50 分别为 9.53 mM 和 1.19 mM。

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Hydralazine Chemical Structure

Hydralazine Chemical Structure

CAS No. : 86-54-4

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Hydralazine 的其他形式现货产品:

Customer Review

Other Forms of Hydralazine:

Hydralazine 相关抗体

Top Publications Citing Use of Products
WB

    Hydralazine purchased from MCE. Usage Cited in: Neurosci Bull. 2020 Oct;36(10):1158-1170.  [Abstract]

    Western blots (left) and analysis (right) of cyto-Drp1, mito-Drp1, and T-Drp1 in different groups of mice. Hydralazine (acrolein scavenger) suppresses the translocation of Drp1 and alleviates the morphological disruption of mitochondria after ICH in mice.

    • 生物活性

    • 纯度 & 产品资料

    • 参考文献

    生物活性

    Hydralazine is a orally active antihypertensive agent, reduces peripheral resistance directly by relaxing the smooth muscle cell layer in arterial vessel. Hydralazine has antioxidant activity, as well as inhibits reactive oxygen species (ROS) release and O2·- generation with an IC50 value of 9.53 mM and 1.19 mM, respectively[1][2].

    IC50 & Target

    IC50: 9.53 mM (ROS), 1.19 mM (O2·-)[1]
    Clinical Trial
    分子量

    160.18

    Formula

    C8H8N4
    CAS 号
    运输条件

    Room temperature in continental US; may vary elsewhere.
    储存方式

    Please store the product under the recommended conditions in the Certificate of Analysis.
    纯度 & 产品资料
    参考文献

    Hydralazine 相关分类

    • 摩尔计算器

    • 稀释计算器

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    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Hydralazine86-54-4Reactive Oxygen Speciesorally activeantihypertensivearterial vesselInhibitorinhibitorinhibit

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