1. Apoptosis
  2. Paraptosis
  3. [Ag(2,2′-bipy)(dppe)][CF3SO3]

[Ag(2,2′-bipy)(dppe)][CF3SO3] 

目录号: HY-157974
产品使用指南

[Ag(2,2′-bipy)(dppe)][CF3SO3] (compound 4) 可以诱导细胞凋亡 (cell paraptosis),可用于耐药卵巢癌的研究。

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[Ag(2,2′-bipy)(dppe)][CF3SO3] Chemical Structure

[Ag(2,2′-bipy)(dppe)][CF3SO3] Chemical Structure

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

[Ag(2,2′-bipy)(dppe)][CF3SO3] (compound 4) can induce cell paraptosis, and can be used for stusy of resistant ovarian cancer[1].

体外研究
(In Vitro)

[Ag(2,2′-bipy)(dppe)][CF3SO3] (compound 4) (0-10 μM,72 h) 抑制 SK-OV-3、SK-OV-3/CBP、HCT116 WT 和 HCT116 WT/OxR 细胞生长,其 IC50 值分别为6.8 μM、5.48 μM、0.70 μM和0.65 μM [1]
[Ag(2,2′-bipy)(dppe)][CF3SO3] (10 μM, 24 h) 诱导 SK-OV-3 和 MES-OV 细胞凋亡[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: SK-OV-3、SK-OV-3/CBP、HCT116 WT and HCT116 WT/OxR cells.
Concentration: 0-10 μM
Incubation Time: 72 h
Result: Inhibited cell growth with the IC50 values of 6.8 μM, 5.48 μM, 0.70 μM and 0.65 μM of SK-OV-3, SK-OV-3/CBP, HCT116 WT and HCT116 WT/OxR , respectively.

Apoptosis Analysis[1]

Cell Line: SK-OV-3 and MES-OV cells
Concentration: 10 μM
Incubation Time: 24 h
Result: Induced cell apoptosis.
分子量

811.54

Formula

C37H32AgF3N2O3P2S-

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

[Ag(2,2′-bipy)(dppe)][CF3SO3] 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
[Ag(2,2′-bipy)(dppe)][CF3SO3]
目录号:
HY-157974
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