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  4. AH22921

AH22921 是一种EP4前列腺素受体拮抗剂，具有在CHO细胞中拮抗前列腺素对腺苷酸环化酶的激活作用的活性。AH22921在CHO细胞中可使PGE?浓度-反应曲线右移，是一种非竞争性拮抗剂，对EP4受体具有选择性，对CHO细胞中的EP4受体有拮抗作用，但不影响含EP2受体的NPE细胞中的PGE?浓度 -反应曲线。

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AH22921 Chemical Structure

AH22921 Chemical Structure

CAS No. : 74480-23-2

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AH22921 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AH22921 is an EP4 prostaglandin receptor antagonist with the activity of antagonizing the activation of adenylate cyclase by prostaglandins in CHO cells. AH22921 can shift the PGE2 concentration-response curve to the right in CHO cells. It is a non-competitive antagonist that is selective for EP4 receptors and has an antagonistic effect on EP4 receptors in CHO cells, but does not affect the PGE2 concentration-response curve in NPE cells containing EP2 receptors.

分子量

477.59

Formula

C29H35NO5
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

AH22921 相关分类

  • 摩尔计算器

  • 稀释计算器

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× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AH2292174480-23-2AH 22921AH-22921OthersInhibitorinhibitorinhibit

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产品名称：
AH22921
目录号：
HY-115827
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