2. Anti-infection
  3. Bacterial
  4. Altersolanol A

Altersolanol A  (Synonyms: Stemphylin; NSC 173943)

目录号: HY-125461
产品使用指南

摩尔计算器

Altersolanol A (Stemphylin; NSC 173943) 对 Bacillus subtilis 和 Pseudomonas aeruginosa 具有抗菌活性，MIC 为 25-100 μg/mL。Altersolanol A 对红豆杉 (Taxus) 无植物毒性 (at dose of 4 μg/μL)。

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Altersolanol A Chemical Structure

Altersolanol A Chemical Structure

CAS No. : 22268-16-2

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规格 价格 是否有货 数量
1 mg ￥3800
4 - 5 周
5 mg   询价  
10 mg   询价  

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Customer Review

Altersolanol A 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Altersolanol A (Stemphylin; NSC 173943) exhibits antimicrobial activities against Bacillus subtilis and Pseudomonas aeruginosa, with MIC of 25-100 μg/mL. Altersolanol A exhibits no phytotoxicity to Taxus (at dose of 4 μg/μL)[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 IC50
> 10 μM
Compound: 8
Cytotoxic activity against human A549 cells by MTT assay
Cytotoxic activity against human A549 cells by MTT assay
[PMID: 25136754]
A549 EC50
> 2 μM
Compound: A
Antiproliferative activity against human A549 cells measured at 6 hrs over 120 hrs by videomicroscopy analysis
Antiproliferative activity against human A549 cells measured at 6 hrs over 120 hrs by videomicroscopy analysis
[PMID: 23664494]
A549 EC50
29.5 μM
Compound: A
Cytotoxicity against human A549 cells after 24 hrs by XTT assay
Cytotoxicity against human A549 cells after 24 hrs by XTT assay
[PMID: 23664494]
B16-F10 IC50
> 10 μM
Compound: 8
Cytotoxic activity against mouse B16F10 cells by MTT assay
Cytotoxic activity against mouse B16F10 cells by MTT assay
[PMID: 25136754]
K562 EC50
> 1 μM
Compound: A
Antiproliferative activity against human K562 cells measured at 6 hrs over 120 hrs by videomicroscopy analysis
Antiproliferative activity against human K562 cells measured at 6 hrs over 120 hrs by videomicroscopy analysis
[PMID: 23664494]
K562 IC50
0.8 μM
Compound: Altersolanol A
Inhibition of NF-kappaB transactivation in TNF-alpha-stimulated human K562 cells preincubated for 2 hrs followed by TNF-alpha challenge measured after 6 hrs by dual luciferase reporter gene assay
Inhibition of NF-kappaB transactivation in TNF-alpha-stimulated human K562 cells preincubated for 2 hrs followed by TNF-alpha challenge measured after 6 hrs by dual luciferase reporter gene assay
[PMID: 24775915]
K562 IC50
0.8 μM
Compound: A
Inhibition of TNFalpha-induced NF-kappa-B transcriptional activity in human K562 cells pretreated with compound for 2 hrs measured 6 hrs post TNFalpha challenge by luciferase reporter gene assay
Inhibition of TNFalpha-induced NF-kappa-B transcriptional activity in human K562 cells pretreated with compound for 2 hrs measured 6 hrs post TNFalpha challenge by luciferase reporter gene assay
[PMID: 23664494]
K562 EC50
2.5 μM
Compound: A
Cytotoxicity against human K562 cells after 48 hrs by trypan blue exclusion test
Cytotoxicity against human K562 cells after 48 hrs by trypan blue exclusion test
[PMID: 23664494]
K562 EC50
4 μM
Compound: A
Cytotoxicity against human K562 cells after 24 hrs by trypan blue exclusion test
Cytotoxicity against human K562 cells after 24 hrs by trypan blue exclusion test
[PMID: 23664494]
PBMC EC50
4.2 μM
Compound: A
Effect on metabolism of human PBMCs after 24 hrs by CellTiter-Glo luminescent cell viability assay
Effect on metabolism of human PBMCs after 24 hrs by CellTiter-Glo luminescent cell viability assay
[PMID: 23664494]
分子量

336.29

Formula

C16H16O8
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Altersolanol A 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Altersolanol A22268-16-2Stemphylin NSC 173943NSC173943NSC 173943NSC-173943BacterialPseudomonas aeruginosaBacillus subtilisInhibitorinhibitorinhibit

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目录号：
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