2. Antibody-drug Conjugate/ADC Related
  3. ADC Linker
  4. Amino-PEG6-amido-bis-PEG5-N3

Amino-PEG6-amido-bis-PEG5-N3 是一种可降解 (cleavable) 的含 11 个单元 PEG 的 ADC linker，可用于合成抗体偶联活性分子 (ADC)。Amino-PEG6-amido-bis-PEG5-N3 是一种点击化学试剂。它含有 Azide 基团，可以和含有 Alkyne 基团的分子发生铜催化的叠氮-炔环加成反应（CuAAc)。它还可以和含有 DBCO 或 BCN 基团的分子发生环张力驱动的炔-叠氮环加成反应 (SPAAC)。

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Amino-PEG6-amido-bis-PEG5-N3 Chemical Structure

Amino-PEG6-amido-bis-PEG5-N3 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
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Amino-PEG6-amido-bis-PEG5-N3 相关抗体

Top Publications Citing Use of Products

查看 ADC Linker 亚型特异性产品:

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Amino-PEG6-amido-bis-PEG5-N3 is a cleavable 11 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Amino-PEG6-amido-bis-PEG5-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC50 & Target

Cleavable Linker

 

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Amino-PEG6-amido-bis-PEG5-N3 相关抗体:
分子量

1147.31

Formula

C48H94N10O21
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Amino-PEG6-amido-bis-PEG5-N3 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Amino-PEG6-amido-bis-PEG5-N3ADC LinkerAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-130957
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