2. Apoptosis
  3. Apoptosis
  4. Anticancer agent 52

Anticancer agent 52 是一种有效的抗癌剂。Anticancer agent 52 显示出体外细胞毒性。Anticancer agent 52 诱导细胞凋亡 (apoptosis)。Anticancer agent 52 显示出抗肿瘤作用。Anticancer agent 52 具有研究膀胱癌的潜力。

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Anticancer agent 52 Chemical Structure

Anticancer agent 52 Chemical Structure

CAS No. : 2388983-64-8

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Anticancer agent 52 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anticancer agent 52 is a potent anticancer agent. Anticancer agent 52 shows in vitro cytotoxicity. Anticancer agent 52 induces apoptosis. Anticancer agent 52 shows antitumor effect. Anticancer agent 52 has the potential for the research of bladder cancer[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
5637 GI50
200 μM
Compound: TPP1
Growth inhibition of human 5637 cells measured after 1 hr by Celltiter-Glo luminescent cell viability assay
Growth inhibition of human 5637 cells measured after 1 hr by Celltiter-Glo luminescent cell viability assay
[PMID: 31718944]
RT-112 GI50
200 μM
Compound: TPP1
Growth inhibition of human RT112 cells measured after 1 hr by Celltiter-Glo luminescent cell viability assay
Growth inhibition of human RT112 cells measured after 1 hr by Celltiter-Glo luminescent cell viability assay
[PMID: 31718944]
RT-4 GI50
150 μM
Compound: TPP1
Growth inhibition of human RT4 cells measured after 1 hr by Celltiter-Glo luminescent cell viability assay
Growth inhibition of human RT4 cells measured after 1 hr by Celltiter-Glo luminescent cell viability assay
[PMID: 31718944]
SW780 GI50
200 μM
Compound: TPP1
Growth inhibition of human SW780 cells measured after 1 hr by Celltiter-Glo luminescent cell viability assay
Growth inhibition of human SW780 cells measured after 1 hr by Celltiter-Glo luminescent cell viability assay
[PMID: 31718944]
TCC-SUP GI50
240 μM
Compound: TPP1
Growth inhibition of human TCCSUP cells measured after 1 hr by Celltiter-Glo luminescent cell viability assay
Growth inhibition of human TCCSUP cells measured after 1 hr by Celltiter-Glo luminescent cell viability assay
[PMID: 31718944]
UMUC3 GI50
80 μM
Compound: TPP1
Growth inhibition of human UM-UC-3 cells measured after 1 hr by Celltiter-Glo luminescent cell viability assay
Growth inhibition of human UM-UC-3 cells measured after 1 hr by Celltiter-Glo luminescent cell viability assay
[PMID: 31718944]
体外研究
(In Vitro)

Anticancer agent 52 (compound TPP1) (0-2048 µM) shows cytotoxicity with IC50s of 200, 200, 150, 200, 240, 80 µM for 5637, RT112, RT4, SWT80, TCCSUP, UMUC3 cells, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Anticancer agent 52 相关抗体:

Apoptosis Analysis[1]

Cell Line: RT112 cells
Concentration: 200 µM
Incubation Time: 1, 2, 4 h
Result: Induced apoptosis with the increased the expression of c-PARP.
分子量

862.67

Formula

C50H43Br2N2P
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Anticancer agent 52 相关分类

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anticancer agent 522388983-64-8Anticancer agent52Anticancer agent-52Apoptosisintravesical instillationRT112 cellsbladder cancerapoptosiscytotoxicityInhibitorinhibitorinhibit

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