2. MAPK/ERK Pathway GPCR/G Protein Metabolic Enzyme/Protease Anti-infection
  3. Ras Farnesyl Transferase Fungal
  4. Antifungal agent 46

Antifungal agent 46 (compound 2f) 是一种有效的抗真菌剂。Antifungal agent 46 通过抑制蛋白质法尼基转移酶 (farnesyltransferase) 来抑制 Ras 信号。

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Antifungal agent 46 Chemical Structure

Antifungal agent 46 Chemical Structure

CAS No. : 2842067-19-8

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Antifungal agent 46 相关抗体

Top Publications Citing Use of Products

查看 Ras 亚型特异性产品:

查看所有亚型
K-Ras H-Ras N-Ras Ras

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antifungal agent 46 (compound 2f) is a potent antifungal agent. Antifungal agent 46 prevents Ras signaling by inhibiting protein farnesyltransferase[1].

体外研究
(In Vitro)

Antifungal agent 46 (compound 2f) inhibits growth at 12.5 μM in biofilm assay, corresponding to a 2-fold higher MIC than Amphotericin B (HY-B0221)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Antifungal agent 46 相关抗体:
体内研究
(In Vivo)

Antifungal agent 46 (compound 2f, 0.78 μM) inhibits FTase activity in vivo[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

565.43

Formula

C26H28BrF3N4O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Antifungal agent 46 相关分类

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antifungal agent 462842067-19-8Antifungal agent46Antifungal agent-46RasFarnesyl TransferaseFungalFtaseCryptoccoccus neoformansRas proteinfarnesyltransferaseantifungalInhibitorinhibitorinhibit

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