2. Anti-infection
  3. Fungal
  4. Antiproliferative agent-18

Antiproliferative agent-18 (Compound 5k) 是一种抗增殖剂，还具有中度抗细菌 (anti-bacterial) 和抗真菌 (anti-fungi) 活性。

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Antiproliferative agent-18 Chemical Structure

Antiproliferative agent-18 Chemical Structure

CAS No. : 2882206-14-4

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Antiproliferative agent-18 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antiproliferative agent-18 (Compound 5k) is an anti-proliferative agent. Antiproliferative agent-18 also displays moderate anti-bacterial and anti-fungi activity[1].

IC50 & Target

Bacteria, Fungi[1]
体外研究
(In Vitro)

Antiproliferative agent-18 (Compound 5k) (200 µg/ /8 mm disc; 24 h for bacteria, 48 h for fungi) 显示中等抑菌活性 (生长抑制区 14-17 毫米)，对酵母样致病真菌 Candida albicans 有中等活性 (生长抑制区 17 毫米)[1]。
Antiproliferative agent-18 (0.1-100 μM; 48 h) 对人前列腺癌 (PC-3)、大肠癌 (HCT-116)、肝细胞癌 (HepG-2)、上皮样宫颈癌 (HeLa) 和乳腺乳腺癌 (MCF-7) 细胞系具有抗增殖活性[1]。
Antiproliferative agent-18 在 SIRT1 酶的活性位点上占据了 NAD 辅因子和组蛋白脱乙酰酶抑制剂 EX527 的位置[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Antiproliferative agent-18 相关抗体:

Cell Proliferation Assay[1]

Cell Line: PC-3, HCT-116, HepG-2, HeLa and MCF-7 cells
Concentration: 0.1-100 μM
Incubation Time: 48 h
Result: Showed anti-proliferative activity with IC50s of 9.71 ± 0.8, 6.47 ± 0.5, 11.27 ± 0.9, 7.09 ± 0.5 and 3.51 ± 0.2 μM against PC-3, HCT-116, HepG-2, HeLa and MCF-7 cells, respectively.
分子量

434.57

Formula

C26H27FN2OS
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Antiproliferative agent-18 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antiproliferative agent-182882206-14-4Antiproliferative agent18Antiproliferative agent 18FungalPC-3HCT-116HepG-2HeLaMCF-7Candida albicansInhibitorinhibitorinhibit

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