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  4. Antitumor agent-65

Antitumor agent-65 (Compound 5) 是 (-)-cleistenolide 的类似物/衍生物。Antitumor agent-65 具有研究癌症疾病的潜力。

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Antitumor agent-65 Chemical Structure

Antitumor agent-65 Chemical Structure

CAS No. : 2456288-82-5

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Antitumor agent-65 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antitumor agent-65 (Compound 5) is an analogue/derivative of (-)-cleistenolide. Antitumor agent-65 has the potential for the research of cancer diseases[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 IC50
8.64 μM
Compound: 5
Antiproliferative activity against human A549 cells assessed as reduction in cell viability measured after 6 days by MTT assay
Antiproliferative activity against human A549 cells assessed as reduction in cell viability measured after 6 days by MTT assay
[PMID: 32653698]
HeLa IC50
4.65 μM
Compound: 5
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability measured after 6 days by MTT assay
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability measured after 6 days by MTT assay
[PMID: 32653698]
HL-60 IC50
1.11 μM
Compound: 5
Antiproliferative activity against human HL-60 cells assessed as reduction in cell viability measured after 6 days by MTT assay
Antiproliferative activity against human HL-60 cells assessed as reduction in cell viability measured after 6 days by MTT assay
[PMID: 32653698]
Jurkat IC50
7.45 μM
Compound: 5
Antiproliferative activity against human Jurkat cells assessed as reduction in cell viability measured after 6 days by MTT assay
Antiproliferative activity against human Jurkat cells assessed as reduction in cell viability measured after 6 days by MTT assay
[PMID: 32653698]
K562 IC50
7.64 μM
Compound: 5
Antiproliferative activity against human K562 cells assessed as reduction in cell viability measured after 6 days by MTT assay
Antiproliferative activity against human K562 cells assessed as reduction in cell viability measured after 6 days by MTT assay
[PMID: 32653698]
MCF7 IC50
5.32 μM
Compound: 5
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability measured after 6 days by MTT assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability measured after 6 days by MTT assay
[PMID: 32653698]
MDA-MB-231 IC50
4.12 μM
Compound: 5
Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability measured after 6 days by MTT assay
Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability measured after 6 days by MTT assay
[PMID: 32653698]
MRC5 IC50
> 100 μM
Compound: 5
Cytotoxicity against human MRC5 cells assessed as reduction in cell viability measured after 6 days by MTT assay
Cytotoxicity against human MRC5 cells assessed as reduction in cell viability measured after 6 days by MTT assay
[PMID: 32653698]
Raji IC50
18.54 μM
Compound: 5
Antiproliferative activity against human Raji cells assessed as reduction in cell viability measured after 6 days by MTT assay
Antiproliferative activity against human Raji cells assessed as reduction in cell viability measured after 6 days by MTT assay
[PMID: 32653698]
分子量

407.33

Formula

C18H17NO10
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Antitumor agent-65 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antitumor agent-652456288-82-5Antitumor agent65Antitumor agent 65OthersInhibitorinhibitorinhibit

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