2. Antibody-drug Conjugate/ADC Related
  3. ADC Linker
  4. Azido-C6-OH

Azido-C6-OH 是一种可降解 (cleavable) 的 ADC linker，可用于合成抗体偶联活性分子 (ADC)。Azido-C6-OH 是一种点击化学试剂。它含有 Azide 基团，可以和含有 Alkyne 基团的分子发生铜催化的叠氮-炔环加成反应（CuAAc)。它还可以和含有 DBCO 或 BCN 基团的分子发生环张力驱动的炔-叠氮环加成反应 (SPAAC)。

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Azido-C6-OH Chemical Structure

Azido-C6-OH Chemical Structure

CAS No. : 146292-90-2

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2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

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规格 价格 是否有货
25 mg ￥300
询问价格 & 货期
50 mg ￥480
询问价格 & 货期
100 mg ￥740
询问价格 & 货期
250 mg ￥1246
询问价格 & 货期
1 g ￥2130
询问价格 & 货期

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Customer Review

Azido-C6-OH 相关抗体

Top Publications Citing Use of Products

查看 ADC Linker 亚型特异性产品:

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Azido-C6-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azido-C6-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC50 & Target

Cleavable Linker

 

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Azido-C6-OH 相关抗体:
分子量

143.19

Formula

C6H13N3O
CAS 号
性状

液体

颜色

Colorless to light yellow

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

纯度: ≥95.0%

COA (277 KB) HNMR (130 KB)

产品使用指南 (1538 KB)
参考文献

Azido-C6-OH 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Azido-C6-OH146292-90-2ADC LinkerAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-138521
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