2. Membrane Transporter/Ion Channel
  3. Sodium Channel
  4. Batrachotoxin

Batrachotoxin (BTX) 是一种强效神经毒素和心脏毒素，存在于哥伦比亚箭毒蛙 (Phyllobates aurotaenia) 皮肤中。Batrachotoxin 作为一种钠离子通道 (sodium channel) 激活剂，通过与细胞膜上的电压门控钠离子通道 (sodium channel) 相互作用，阻断钠离子通道 (sodium channel) 的正常关闭，导致钠离子持续流入细胞内，从而引起细胞的持续去极化。

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Batrachotoxin Chemical Structure

Batrachotoxin Chemical Structure

CAS No. : 23509-16-2

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Batrachotoxin 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Batrachotoxin (BTX) is a potent neurotoxin and cardiotoxin found in the skin of the Colombian poison dart frog (Phyllobates aurotaenia). Batrachotoxin is a sodium channel activator that interacts with voltage-gated sodium channels on the cell membrane, blocking the normal closure of sodium channels, causing a continuous influx of sodium ions into the cell, thereby causing a sustained depolarization of the cell[1].

分子量

538.67

Formula

C31H42N2O6
CAS 号
结构分类
初始来源

Phyllobates aurotaenia
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Batrachotoxin 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

Batrachotoxin23509-16-2BTXSodium ChannelNa channelsNa+ channelsNeurotoxinheart toxinssodium channeldepolarizationactivatorInhibitorinhibitorinhibit

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