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  3. BMD4503-2

BMD4503-2 是喹喔啉 (quinoxaline) 衍生物,具有抑制 LRP5/6-sclerostin 相互作用的活性。BMD4503-2 通过竞争性结合到 LRP5/6-sclerostin 复合体,恢复了 Wnt/β-catenin 信号通路的活性。BMD4503-2 可用于 Wnt 信号通路在骨骼发育,维持以及骨质疏松症的研究。

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BMD4503-2 Chemical Structure

BMD4503-2 Chemical Structure

CAS No. : 301357-87-9

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

BMD4503-2 is a quinoxaline derivative with inhibitory activity against LRP5/6-sclerostin interactions. BMD4503-2 restores the activity of the Wnt/β-catenin signaling pathway by competitively binding to the LRP5/6-sclerostin complex. BMD4503-2 can be used in the study of Wnt signaling pathways in bone development, maintenance and osteoporosis[1].

分子量

483.54

Formula

C26H21N5O3S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

BMD4503-2 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
BMD4503-2
目录号:
HY-125146
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