2. PROTAC Antibody-drug Conjugate/ADC Related
  3. PROTAC Linkers ADC Linker
  4. Bromoacetamido-PEG4-acid

Bromoacetamido-PEG4-acid 

目录号: HY-141382 纯度: 96.82%
COA 产品使用指南

摩尔计算器

Bromoacetamido-PEG4-acid 是一种 PROTAC linker，属于 PEG 类。可用于合成PROTAC分子。Bromoacetamido-PEG4-acid 也是一种可降解 (cleavable) 的含 4 个单元 PEG 的 ADC linker，可用于合成抗体偶联活性分子 (ADC)。

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Bromoacetamido-PEG4-acid Chemical Structure

Bromoacetamido-PEG4-acid Chemical Structure

CAS No. : 1807518-67-7

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规格 价格 是否有货 数量
100 mg ￥235
In-stock
250 mg ￥520
In-stock
500 mg ￥930
In-stock
1 g ￥1760
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Bromoacetamido-PEG4-acid 相关抗体

Top Publications Citing Use of Products

查看 PROTAC Linkers 亚型特异性产品:

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PEG Linkers Alkyl-Chain Linkers Alkyl/ether Linkers

查看 ADC Linker 亚型特异性产品:

查看所有亚型
Cleavable Linker Non-cleavable Linker Acid Cleavable Linker Disulfide Cleavable Linker Protease Cleavable Linker Glycosidase Cleavable Linker Phosphatase Cleavable Linker

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Bromoacetamido-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Bromoacetamido-PEG4-acid is also a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].

IC50 & Target

PEGs

 

Cleavable Linker

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Bromoacetamido-PEG4-acid 相关抗体:
分子量

386.24

Formula

C13H24BrNO7
CAS 号
性状

粘稠液体

颜色

Colorless to light yellow

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

纯度: 96.82%

COA (279 KB) LCMS (90 KB)

产品使用指南 (1538 KB)
参考文献

Bromoacetamido-PEG4-acid 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bromoacetamido-PEG4-acid1807518-67-7PROTAC LinkersADC LinkerAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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目录号：
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