1. GPCR/G Protein Neuronal Signaling
  2. Neuropeptide Y Receptor
  3. CART (1-39), Human, Rat

CART (1-39), Human, Rat 是由 CART 肽的 1-39 个残基组成的神经肽。CART (1-39), Human, Rat 是一种具有强烈抑制食欲的鼠源饱腹感因子,与瘦素和神经肽 Y 密切相关。CART (1-39), Human, Rat 抑制正常和饥饿诱导的摄食。CART (1-39), Human, Rat 可诱导焦虑和压力相关行为。

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Custom Peptide Synthesis

CART (1-39), Human, Rat Chemical Structure

CART (1-39), Human, Rat Chemical Structure

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查看 Neuropeptide Y Receptor 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CART (1-39), Human, Rat is a neuropeptide consisting of 1-39 residues of the CART peptide. CART (1-39), Human, Rat is a rat satiety factor with potent appetite-suppressing activity and is closely associated with leptin and neuropeptide Y. CART (1-39), Human, Rat inhibits both normal and starvation-induced feeding. CART (1-39), Human, Rat can induce anxiety and stress-related behavior[1].

体外研究
(In Vitro)

CART (1-39), Human, Rat (100 nM) increases intracellular calcium concentrations in rat cortical neurons[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

CART (1-39), Human, Rat (0.05-2 nM; Intrathecal injection; Sprague-Dawley rats) can not cause a significant change of blood pressure or heart rate, but potentiates the pressor effects of glutamate injected intrathecally in anesthetized rats[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Adult male Sprague-Dawley rats[1]
Dosage: 0.05, 0.5, and 2 nM
Administration: Intrathecal injection
Result: Potentiated glutamate-induced tachycardiac effects at a higher dose of in some of the rats.
分子量

4369.76

Formula

C188H303N57O63

Sequence Shortening

{Glp}-EDAELQPRALDIYSAVDDASHEKELPRRQLRAPGAVLQ

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
CART (1-39), Human, Rat
目录号:
HY-P3691
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