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  4. COR627

COR627是一种GABA受体正向变构调节剂，具有增强GABA的活性。COR627在大鼠皮层膜中表现出对GABA和baclofen刺激的作用，能够提高其对GABA(B)受体的亲和力。COR627在体内实验中显示，预处理无效剂量的COR627能够增强baclofen的镇静/催眠效果。

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COR627 Chemical Structure

COR627 Chemical Structure

CAS No. : 329221-34-3

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COR627 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

COR627 is a GABA receptor positive allosteric modulator with the ability to enhance GABA activity. COR627 exhibits effects on GABA and baclofen stimulation in rat cortical membranes and can increase its affinity for GABA(B) receptors. In vivo experiments have shown that COR627 can enhance the sedative/hypnotic effects of baclofen at pretreatment ineffective doses[1].

分子量

361.50

Formula

C20H27NO3S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

COR627 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

COR627329221-34-3COR 627COR-627OthersInhibitorinhibitorinhibit

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